{"created":"2023-07-27T06:56:26.314877+00:00","id":53278,"links":{},"metadata":{"_buckets":{"deposit":"f2d268d9-cf75-4eb3-9740-096de1db89e6"},"_deposit":{"created_by":18,"id":"53278","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53278"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053278","sets":["2812:2813:2818"]},"author_link":["94664"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-06-08","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2013-04-01 – 2016-03-31","bibliographic_titles":[{"bibliographic_title":"平成27(2015)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2015 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"細胞周期をリアルタイムで観察できる蛍光蛋白”Fucci”を導入したヒト骨肉腫細胞株143Bにin vitroでシスプラチン・ドキソルビシンを作用させリアルタイムイメージングを行った。その結果、細胞周期による抗がん剤の感受性の違い、抗がん剤の種類によるアポトーシスの起こり方の違いや細胞周期停止の様子を明らかにできた。","subitem_description_type":"Abstract"},{"subitem_description":"we utilized the fluorescence ubiquitination-based cell cycle indicator (FUCCI) imaging system to investigate the correlation between cell-cycle behavior and apoptosis after treatment of osteosarcoma cells with chemotherapeutic drugs.\nOsteosarcoma cell line 143B expressing FUCCI were treated with doxorubicin or cisplatinum, and we revealed that apoptosis behavior, cell cycle arrest, and chemotherapy sensitivity depending on cell cycle differs in each chemotherapy drugs.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:25861301, 研究期間(年度):2013-04-01 – 2016-03-31","subitem_description_type":"Other"},{"subitem_description":"出典:研究課題「抗癌剤耐性や肺転移形成と細胞周期との関連: Fucci導入肉腫細胞を用いた解析」課題番号25861301\n(KAKEN:科学研究費助成事業データベース(国立情報学研究所)) \n(https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-25861301/25861301seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"名古屋市立大学 / 金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059562","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=50608693"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=50608693","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-25861301/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-25861301/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-25861301/25861301seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-25861301/25861301seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-08"}],"displaytype":"detail","filename":"ME-PR-KIMURA-H-kaken 2016-4p.pdf","filesize":[{"value":"148.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-KIMURA-H-kaken 2016-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53278/files/ME-PR-KIMURA-H-kaken 2016-4p.pdf"},"version_id":"083747d1-1293-4aa1-b698-78312a3425f2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"抗癌剤耐性や肺転移形成と細胞周期との関連: Fucci導入肉腫細胞を用いた解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"抗癌剤耐性や肺転移形成と細胞周期との関連: Fucci導入肉腫細胞を用いた解析"},{"subitem_title":"Correlation between cell cycle and chemotherapy resistance and lung metastases: Analysis using Fucci transfected sarcoma cells","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2818"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-10-08"},"publish_date":"2020-10-08","publish_status":"0","recid":"53278","relation_version_is_last":true,"title":["抗癌剤耐性や肺転移形成と細胞周期との関連: Fucci導入肉腫細胞を用いた解析"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T10:51:52.976210+00:00"}