{"created":"2023-07-27T06:56:27.429999+00:00","id":53293,"links":{},"metadata":{"_buckets":{"deposit":"f1fb55e0-7b68-4d49-a44f-58f58dfc3433"},"_deposit":{"created_by":18,"id":"53293","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53293"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053293","sets":["2812:2813:2823"]},"author_link":["45196","94679"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-05-25","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2009 – 2010","bibliographic_titles":[{"bibliographic_title":"平成22(2010)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2010 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ラット網膜において、2孔型KチャンネルのmRNA発現がみられ、組織学的にTRAAKとTREK-2の発現が確認された。ただし、パッチクランプ法ではそのイオン電流は記録できなかった。一方、ブタ毛様体上皮ではKCNQチャンネル電流が記録された。毛様体ではKCNQ1,4,5のmRNAが優位に発現していた。","subitem_description_type":"Abstract"},{"subitem_description":"The mRNA of two pore-domain potassium channel (K(2P)) was detected, and immunohistochemical findings showed TRAAK and TREK-2 expressions in the rat retina. However, patch-clamp study failed to detect K(2P) currents in isolated retinal cells. A KCNQ channel current was identified in porcine ciliary epithelial cells. Molecular biological analysis revealed that mRNAs of KCNQ1, 4 and 5 were expressed dominantly in ciliary body.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:21791674, 研究期間(年度):2009-2010","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「網膜における2孔型Kチャンネルの機能発現とその神経保護作用」課題番号21791674\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21791674/21791674seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059577","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=80377390"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=80377390","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-21791674/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-21791674/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21791674/21791674seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21791674/21791674seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-08"}],"displaytype":"detail","filename":"ME-PR-SAKURADA-N-kaken 2011-5p.pdf","filesize":[{"value":"356.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-SAKURADA-N-kaken 2011-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53293/files/ME-PR-SAKURADA-N-kaken 2011-5p.pdf"},"version_id":"9ce25562-96c0-4a70-83cd-77fef724964e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"網膜における2孔型Kチャンネルの機能発現とその神経保護作用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"網膜における2孔型Kチャンネルの機能発現とその神経保護作用"},{"subitem_title":"Two pore-domain potassium channel in retina: its functional expression and role of neuroprotection.","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2823"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-10-08"},"publish_date":"2020-10-08","publish_status":"0","recid":"53293","relation_version_is_last":true,"title":["網膜における2孔型Kチャンネルの機能発現とその神経保護作用"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:22:56.023876+00:00"}