{"created":"2023-07-27T06:56:29.114732+00:00","id":53319,"links":{},"metadata":{"_buckets":{"deposit":"5e69bbe1-8d9a-4153-aac6-3c1c18fbc9dd"},"_deposit":{"created_by":18,"id":"53319","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53319"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053319","sets":["2812:2813:2822"]},"author_link":["24565","94705"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05-11","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2009 – 2011","bibliographic_titles":[{"bibliographic_title":"平成23(2011)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2011 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"口腔扁平上皮癌におけるMaspinは64.8%に陽性所見を認めたが、陽性症例では陰性症例に比べて生命予後が良好であった。一方で、高度浸潤能を持つがん浸潤様式(山本・小浜分類) 4D型ではMaspin発現の減弱を認めた。また、uPA/uPARシステムにおけるMaspin発現は、uPA/uPAR発現と逆相関し、uPA(+)/uPAR(+)/Maspin(-)の場合に最も浸潤能が強く、生命予後が最も悪い組み合わせであることが判明した。","subitem_description_type":"Abstract"},{"subitem_description":"Maspin expression in oral squamous cell carcinoma(OSCC) was detected in 64.8%. Patients with positive maspin expression had a significantly better prognosis. In contrast, maspin expression was lower in mode of invasion(Yamamoto-Kohama Critria) 4D type with high invasive potential. Moreover, Maspin expression showed a negative correlation with uPA/uPAR expression in the uPA/uPAR system. Expression pattern, uPA(+)/uPAR(+)/Maspin(-), exhibited a stronger invasive potential and the worst survival rate than other invasive grades of OSCC.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:21791982, 研究期間(年度):2009-2011","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「Maspin機能発現による口腔扁平上皮癌の浸潤・転移抑制効果の実験的研究」課題番号21791982\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21791982/21791982seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059603","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=60452108"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=60452108","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-21791982/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-21791982/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21791982/21791982seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21791982/21791982seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-05"}],"displaytype":"detail","filename":"HO-PR-YOSHIZAWA-K-kaken 2012-5p.pdf","filesize":[{"value":"243.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-YOSHIZAWA-K-kaken 2012-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53319/files/HO-PR-YOSHIZAWA-K-kaken 2012-5p.pdf"},"version_id":"5bb059a0-b522-498c-9d1c-23115a55ccb7"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"Maspin機能発現による口腔扁平上皮癌の浸潤・転移抑制効果の実験的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Maspin機能発現による口腔扁平上皮癌の浸潤・転移抑制効果の実験的研究"},{"subitem_title":"Suppressive effect of invasion and metastasis of oral squamous cell carcinoma by maspin expression","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2822"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-10-05"},"publish_date":"2020-10-05","publish_status":"0","recid":"53319","relation_version_is_last":true,"title":["Maspin機能発現による口腔扁平上皮癌の浸潤・転移抑制効果の実験的研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:25:14.286486+00:00"}