{"created":"2023-07-27T06:56:29.181501+00:00","id":53320,"links":{},"metadata":{"_buckets":{"deposit":"876041e4-3e41-4da8-8394-17f391aed92f"},"_deposit":{"created_by":18,"id":"53320","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53320"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053320","sets":["2812:2813:2819"]},"author_link":["74114","621"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-06-04","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2012-04-01 – 2015-03-31","bibliographic_titles":[{"bibliographic_title":"平成26(2014)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2014 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Demura, Satoru"}],"nameIdentifiers":[{"nameIdentifier":"74114","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00348228","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=00348228"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"脊椎腫瘍切除後の動物モデルで、脂肪由来幹細胞を脊椎骨欠損部での再建材料として用い、移植骨の骨形成への関わりを評価した。その結果、移植骨内に占める線維性結合組織面積、新生骨に占める層板骨の割合、骨形成速度の比較検討で、いずれも脂肪由来幹細胞群は対照群と比較して高値となった。移植骨の骨形成は線維性結合組織の増生に始まり、リモデリングを経て骨癒合に至るとされる。脂肪由来幹細胞群では対照群より早期の段階で層板骨が形成され、骨形成を促進させることができると考えられた。","subitem_description_type":"Abstract"},{"subitem_description":"We investigated whether adipose derived regenerative cells (ADRCs) promote osteogenesis of the bone graft in total en bloc spondylectomy (TES) animal model. In control group, bone formation area was occupied by woven bone 2 weeks after surgery. In ADRCs group, lamellar bone was shown in a certain proportion 2 weeks after surgery, and the ratio of lamellar bone increased in both groups 4weeks after sugery. The Number of osteoblasts lined up on the osteoid surface tended to be large in ADRCs group. Under fluorescent light, there was few deposition of calcein in control group, in the meanwhile, there were defuse deposition which showed immature lamellar structure in ADRCs group 2 weeks after surgery. The orderly label line was shown that meant mature lamellar structure in both groups 4weeks after surgery. ADRCs used as materials of spinal reconstruction promoted osteogenesis of the bone graft in the early phase.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:24592190, 研究期間(年度):2012-04-01 – 2015-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「腫瘍脊椎骨全摘術後の骨欠損に対する自己脂肪由来幹細胞を用いた骨再生」課題番号24592190\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-24592190/24592190seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059604","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=00348228"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=00348228","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-24592190/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-24592190/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-24592190/24592190seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-24592190/24592190seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"出村, 諭"}],"nameIdentifiers":[{"nameIdentifier":"621","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00348228","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=00348228"},{"nameIdentifier":"00348228","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000000348228"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-26"}],"displaytype":"detail","filename":"HO-PR-DEMURA-S-kaken 2015-6p.pdf","filesize":[{"value":"368.7 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-DEMURA-S-kaken 2015-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53320/files/HO-PR-DEMURA-S-kaken 2015-6p.pdf"},"version_id":"d115db52-db7c-4489-b454-fd78e83e4072"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"腫瘍脊椎骨全摘術後の骨欠損に対する自己脂肪由来幹細胞を用いた骨再生","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腫瘍脊椎骨全摘術後の骨欠損に対する自己脂肪由来幹細胞を用いた骨再生"},{"subitem_title":"Bone healing with the adipose-derived regenerative cells in the large bone defect after total en bloc spondylectomy","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2819"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-10-26"},"publish_date":"2020-10-26","publish_status":"0","recid":"53320","relation_version_is_last":true,"title":["腫瘍脊椎骨全摘術後の骨欠損に対する自己脂肪由来幹細胞を用いた骨再生"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-07-01T05:49:29.996405+00:00"}