{"created":"2023-07-27T06:56:29.314341+00:00","id":53322,"links":{},"metadata":{"_buckets":{"deposit":"3e4fd47c-24c6-4e4a-a2c5-a25cd0bb1f32"},"_deposit":{"created_by":18,"id":"53322","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53322"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053322","sets":["2812:2813:2824"]},"author_link":["33"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-05-26","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2007 – 2009","bibliographic_titles":[{"bibliographic_title":"平成21(2009)年度 科学研究費補助金 基盤研究(B) 研究成果報告書"},{"bibliographic_title":"2009 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ガラクトース転移酵素やシアル酸合成酵素の遺伝子改変マウスを解析することにより,IgA腎症やネフローゼの発症に糖鎖異常が関わっていることを明らかにした。また,ガラクトース含有糖鎖はその種類によって,空間学習・記憶や協調運動などの高次脳機能や初期発生にも重要な役割を担っていることを明らかにした。これらの成果は糖鎖の生物学的重要性を示すと共に,ヒト疾患の診断や治療に応用できると考えられる。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19300144, 研究期間(年度):2007 – 2009","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「糖鎖異常に起因するヒト疾患モデルマウスの開発と発症機構の解析」課題番号19300144\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19300144/19300144seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学学際科学実験センター","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059606","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=50251450"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=50251450","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19300144/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19300144/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19300144/19300144seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19300144/19300144seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-26"}],"displaytype":"detail","filename":"FR-PR-ASANO-M-kaken 2010-5p.pdf","filesize":[{"value":"524.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"FR-PR-ASANO-M-kaken 2010-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53322/files/FR-PR-ASANO-M-kaken 2010-5p.pdf"},"version_id":"887e7c1e-2b14-4d25-889e-2d1385d9d3a2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"糖鎖異常に起因するヒト疾患モデルマウスの開発と発症機構の解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"糖鎖異常に起因するヒト疾患モデルマウスの開発と発症機構の解析"},{"subitem_title":"Development of mouse models for human diseases caused by impaired glycosylation and analysis of their mechanisms","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2824"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-10-26"},"publish_date":"2020-10-26","publish_status":"0","recid":"53322","relation_version_is_last":true,"title":["糖鎖異常に起因するヒト疾患モデルマウスの開発と発症機構の解析"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:11:58.689498+00:00"}