{"created":"2023-07-27T06:56:31.266993+00:00","id":53352,"links":{},"metadata":{"_buckets":{"deposit":"34a5469c-addd-4bf8-9b49-0fe4bbd0de40"},"_deposit":{"created_by":18,"id":"53352","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53352"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053352","sets":["2812:2813:2821"]},"author_link":["35","27186"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04-16","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2009 – 2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 基盤研究(B) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"水試料中のPAH,NPAH類を対象にHPLC/蛍光検出法,HPLC/化学発光検出法を用いた超高感度分析法を開発し,前者を用いて日本海及び周辺海域のPAH汚染の現状を明らかにした。また,PAH水酸化体とPAHキノン体の酵母two-hybrid法を用いた内分泌かく乱作用とキンギョ鱗培養システムに及ぼす影響に関連があり,作用を示す化合物との間に構造活性相関があることを明らかにした。","subitem_description_type":"Abstract"},{"subitem_description":"Analytical methods for PAHs and NPAHs in water were developed by the HPLC/fluorescence detection and HPLC/chemiluminescence detection, respectively. The contamination of PAHs in the Japan Sea and surrounding areas was clarified by using the former method. Endocrine disrupting activities of hydroxy PAHs and quinoid PAHs were evaluated by using the east two-hybrid assay and goldfish-scale incubator assay. The active compounds by the assay systems showed a structure-activity relationship.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:21390034, 研究期間(年度):2009 – 2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「多環芳香族炭化水素類が環境・生体で新たに獲得する毒性に関する戦略研究」課題番号21390034\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21390034/21390034seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域薬学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059635","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=40115267"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=40115267","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-21390034/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-21390034/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21390034/21390034seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-21390034/21390034seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-11-02"}],"displaytype":"detail","filename":"PH-PR-HAYAKAWA-K-kaken 2013-6p.pdf","filesize":[{"value":"410.7 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"PH-PR-HAYAKAWA-K-kaken 2013-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53352/files/PH-PR-HAYAKAWA-K-kaken 2013-6p.pdf"},"version_id":"f643f1b3-e291-41ca-983b-8e8f5d0a17e2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"多環芳香族炭化水素類が環境・生体で新たに獲得する毒性に関する戦略研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"多環芳香族炭化水素類が環境・生体で新たに獲得する毒性に関する戦略研究"},{"subitem_title":"Strategic Study on Environmentally and/or Biologically ExpressingToxicity of Polycyclic Aromatic Hydrocarbons","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-11-02"},"publish_date":"2020-11-02","publish_status":"0","recid":"53352","relation_version_is_last":true,"title":["多環芳香族炭化水素類が環境・生体で新たに獲得する毒性に関する戦略研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:07:06.492267+00:00"}