{"created":"2023-07-27T06:56:37.832911+00:00","id":53504,"links":{},"metadata":{"_buckets":{"deposit":"155430b7-38db-4559-af9c-0f0dbc9a39af"},"_deposit":{"created_by":18,"id":"53504","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53504"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053504","sets":["2812:2813:2823"]},"author_link":["22249","69866"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-04-04","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2008 – 2010","bibliographic_titles":[{"bibliographic_title":"平成22(2010)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2010 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"核にGFP、細胞質にRFPが発現した2色のがん細胞を用い、マウスの血管内に転移巣を形成させ、抗癌剤投与もしくは紫外線照射によりがん細胞の細胞死を誘導して、その形態的違いについてin vivoでの観察を行った。その結果、アポトーシスとネクローシスという2つのカテゴリーでは分類しきれない数種類の細胞死の形態が存在する事が観察できた。またがん細胞の種類や投与する抗癌剤の種類、照射する放射線の波長により、それらに違いがあることが分かった。","subitem_description_type":"Abstract"},{"subitem_description":"We observed morphology of in vivo cell death, induced by anti-cancer agent or ultraviolet light, using dual-color cancer cells in which GFP was expressing in nucleus and RFP in cytoplasm. As results, we found several morphologies of cell death, even though there is usually said to be only two categories for cell death, apoptosis and necrosis. We also found that those morphologic differences were dependent on cell line, anti-cancer drug, and wave length of radiation.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:20590307, 研究期間(年度):2008 – 2010","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「生体内における化学療法・放射線療法による形態学的癌細胞死のリアルタイム画像検証」課題番号20590307\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-20590307/20590307seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059786","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=20397186"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=20397186","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-20590307/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-20590307/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-20590307/20590307seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-20590307/20590307seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-11-26"}],"displaytype":"detail","filename":"ME-PR-SHIRAI-T-kaken 2011-6p.pdf","filesize":[{"value":"243.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-SHIRAI-T-kaken 2011-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53504/files/ME-PR-SHIRAI-T-kaken 2011-6p.pdf"},"version_id":"1f575892-4689-432e-bd63-249e5aeea91b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"生体内における化学療法・放射線療法による形態学的癌細胞死のリアルタイム画像検証","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"生体内における化学療法・放射線療法による形態学的癌細胞死のリアルタイム画像検証"},{"subitem_title":"Real time imaging & morphological analysis of cell death induced by chemotherapy & radiotherapy in vivo","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2823"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-11-26"},"publish_date":"2020-11-26","publish_status":"0","recid":"53504","relation_version_is_last":true,"title":["生体内における化学療法・放射線療法による形態学的癌細胞死のリアルタイム画像検証"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:23:11.969083+00:00"}