{"created":"2023-07-27T06:56:43.945615+00:00","id":53644,"links":{},"metadata":{"_buckets":{"deposit":"487a941b-c397-4f94-8390-3d0a1ffdf1dc"},"_deposit":{"created_by":18,"id":"53644","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53644"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053644","sets":["2812:2813:2825"]},"author_link":["2653","77197"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-05-13","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2007 – 2008","bibliographic_titles":[{"bibliographic_title":"平成20(2008)年度 科学研究費補助金 基盤研究(B) 研究成果報告書"},{"bibliographic_title":"2008 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakao, Shinji"}],"nameIdentifiers":[{"nameIdentifier":"77197","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70217660","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70217660"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"再生不良性貧血(再不貧)における新たな自己抗原を同定するため、造血幹細胞由来の蛋白を再不貧患者血清と反応させたところ、heterogenous nuclear ribonucleoprotein(hnRNPK)に対する抗体が同定された。この抗hnRNP抗体は自己免疫性再生不良性貧血(再不貧)で高頻度に検出されることが明らかになった。この抗体は再不貧患者の約30%に検出され、陽性患者では免疫抑制療法に対する反応性が、陰性患者に比べて有意に高かった。したがって本抗体は再不貧における免疫病態の良いマーカーと考えられた。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19390260, 研究期間(年度):2007 – 2008","subitem_description_type":"Other"},{"subitem_description":"出典：「自己抗体とCLIP置換型Ii鎖ライブラリーを利用した再生不良性貧血自己抗原の同定」研究成果報告書　課題番号19390260\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19390260/19390260seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059926","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=70217660"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=70217660","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19390260/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19390260/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19390260/19390260seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19390260/19390260seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中尾, 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