{"created":"2023-07-27T06:56:44.303328+00:00","id":53653,"links":{},"metadata":{"_buckets":{"deposit":"3ee3cb30-b5ca-4b14-a835-d1d6d281deaf"},"_deposit":{"created_by":18,"id":"53653","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53653"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053653","sets":["2812:2813:2825"]},"author_link":["342"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-04-10","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2007 – 2008","bibliographic_titles":[{"bibliographic_title":"平成20(2008)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2008 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nohara, Atsushi"}],"nameIdentifiers":[{"nameIdentifier":"342","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50313648","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50313648"},{"nameIdentifier":"50313648","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=50313648"},{"nameIdentifier":"50313648","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000050313648"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"核内受容体は関連した遺伝子群を協調して制御する転写因子で, Retinoid-X-receptor(RXR)とヘテロダイマー形成する核内受容体群は脂質および糖質代謝を制御する.我々はこれらの核内受容体群の遺伝子変異検索を行い, 同定された変異の機能解析を行った.その結果いくつもの遺伝子変異が本邦において存在し, これらが脂質および糖代謝異常症における遺伝的背景になっていること, また薬物治療においてその効果を規定する因子となっていることを解明した。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19591040, 研究期間(年度):2007 – 2008","subitem_description_type":"Other"},{"subitem_description":"出典：「代謝関連核内受容体による冠動脈危険因子制御の解明と治療」研究成果報告書　課題番号19591040\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19591040/19591040seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059935","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=50313648"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=50313648","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19591040/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19591040/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19591040/19591040seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19591040/19591040seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"野原, 淳"}],"nameIdentifiers":[{"nameIdentifier":"342","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50313648","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50313648"},{"nameIdentifier":"50313648","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=50313648"},{"nameIdentifier":"50313648","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000050313648"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-11-30"}],"displaytype":"detail","filename":"ME-PR-NOHARA-A-kaken 2009-5p.pdf","filesize":[{"value":"266.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-NOHARA-A-kaken 2009-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53653/files/ME-PR-NOHARA-A-kaken 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