{"created":"2023-07-27T06:56:55.491202+00:00","id":53921,"links":{},"metadata":{"_buckets":{"deposit":"eb486910-41fd-4bf7-8094-c2b017b65add"},"_deposit":{"created_by":18,"id":"53921","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53921"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053921","sets":["2812:2813:2824"]},"author_link":["95219"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-04-04","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2005 – 2009","bibliographic_titles":[{"bibliographic_title":"平成21(2009)年度 科学研究費補助金 特定領域研究 研究成果報告書"},{"bibliographic_title":"2009 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ともに重篤な軟部組織感染症(ヒト喰いバクテリア)を引き起こすウェルシュ菌とA群レンサ球菌について、ゲノム配列解析やDNAマイクロアレイによる遺伝子発現解析を精力的に進め、それぞれの菌における、non-coding RNAの病原性への関与などの共通性や、ゲノムの持つ特徴や病原遺伝子発現制御系の違いをなど明らかにした。これらの研究成果は外部からの遺伝子発現制御という新規戦略において重要なものであり、今後感染症を予防・治療する上でのターゲット分子の特定に役立つ知見が得られた。","subitem_description_type":"Abstract"},{"subitem_description":"In Clostridium perfringens and Streptococcus pyogenes, both of which causes severe soft-tissue infection (flesh-eating bacteria), we proceed comprehensive analyses by genome sequencing and DNA microarray experiments. We found that these bacteria share common mechanism using small non-coding RNA for the control of virulence expression and that both have different unique mechanism for genome maintenance and total regulatory system for virulence control. These research would be important for finding molecular targets for prevention and/or therapy, which will lead to the innovation of new bacterial infection control.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:17019021, 研究期間(年度):2005 – 2009","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「細菌による致死的軟部組織感染症の発症機構の解明および予防・治療への応用」課題番号17019021\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17019021/17019021seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00060201","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=80235655"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=80235655","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-17019021/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-17019021/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17019021/17019021seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17019021/17019021seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-10"}],"displaytype":"detail","filename":"ME-PR-SHIMIZU-T-kaken 2010-6p.pdf","filesize":[{"value":"291.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-SHIMIZU-T-kaken 2010-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53921/files/ME-PR-SHIMIZU-T-kaken 2010-6p.pdf"},"version_id":"45f7f5cc-5744-49de-b0b4-3741f93ca245"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"細菌による致死的軟部組織感染症の発症機構の解明および予防・治療への応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"細菌による致死的軟部組織感染症の発症機構の解明および予防・治療への応用"},{"subitem_title":"Analysis in pathogenesis of bacterial lethal soft-tissue infection and application to prevention and therapy.","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2824"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-12-10"},"publish_date":"2020-12-10","publish_status":"0","recid":"53921","relation_version_is_last":true,"title":["細菌による致死的軟部組織感染症の発症機構の解明および予防・治療への応用"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:12:33.381322+00:00"}