{"_buckets": {"deposit": "fff867f7-2b7d-48e8-a496-04db57458993"}, "_deposit": {"created_by": 18, "id": "55454", "owners": [18], "pid": {"revision_id": 0, "type": "depid", "value": "55454"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00055454", "sets": ["1134"]}, "author_link": ["97278", "22121", "71115", "929", "22865", "249", "76766", "20299", "129", "61653", "62", "97271", "76768", "182", "74993", "2514", "642"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2014", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "13", "bibliographicPageEnd": "3608", "bibliographicPageStart": "3597", "bibliographicVolumeNumber": "20", "bibliographic_titles": [{"bibliographic_title": "World Journal of Gastroenterology"}]}]}, "item_4_creator_33": {"attribute_name": "著者別表示", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "小林, 水緒"}], "nameIdentifiers": [{"nameIdentifier": "61653", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "原田, 憲一"}], "nameIdentifiers": [{"nameIdentifier": "182", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "30283112", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=30283112"}, {"nameIdentifier": "30283112", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=30283112"}, {"nameIdentifier": "30283112", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000030283112"}]}, {"creatorNames": [{"creatorName": "佐藤, 保則"}], "nameIdentifiers": [{"nameIdentifier": "249", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "30324073", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=30324073"}, {"nameIdentifier": "30324073", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=30324073"}, {"nameIdentifier": "30324073", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000030324073"}]}, {"creatorNames": [{"creatorName": "佐々木, 素子"}], "nameIdentifiers": [{"nameIdentifier": "129", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70225895", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=70225895"}, {"nameIdentifier": "70225895", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=70225895"}, {"nameIdentifier": "70225895", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000070225895"}]}, {"creatorNames": [{"creatorName": "池田, 博子"}], "nameIdentifiers": [{"nameIdentifier": "642", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "10447675", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10447675"}, {"nameIdentifier": "10447675", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=10447675"}, {"nameIdentifier": "10447675", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000010447675"}]}, {"creatorNames": [{"creatorName": "金子, 周一"}], "nameIdentifiers": [{"nameIdentifier": "62", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60185923", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60185923"}, {"nameIdentifier": "60185923", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=60185923"}, {"nameIdentifier": "60185923", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000060185923"}]}, {"creatorNames": [{"creatorName": "中沼, 安二"}], "nameIdentifiers": [{"nameIdentifier": "2514", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "10115256", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10115256"}, {"nameIdentifier": "10115256", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000010115256"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "AIM: To investigate histological and immunohistochemical differences in hepatitis between autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) with AIH features. METHODS: Liver needle biopsies of 41 PBC with AIH features and 43 AIH patients were examined. The activity of periportal and lobular inflammation was scored 0 (none or minimal activity) to 4 (severe), and the degree of hepatitic rosette formation and emperipolesis was semiquantatively scored 0-3. The infiltration of mononuclear cells positive for CD20, CD38, CD3, CD4, and CD8 and positive for immunoglobulins (IgG, IgM, and IgA) at the periportal areas (interface hepatitis) and in the hepatic lobules (lobular hepatitis) were semiquantitatively scored in immunostained liver sections (score 0-6). Serum aspartate aminotransferase (AST), immunoglobulins, and autoantibodies at the time of liver biopsy were correlated with the histological and immunohistochemical scores of individual lesions. RESULTS: Lobular hepatitis, hepatitic rosette formation, and emperipolesis were more extensive and frequent in AIH than in PBC. CD3+, CD4+, and CD8+ cell infiltration scores were higher in the hepatic lobules and at the interface in AIH but were also found in PBC. The degree of mononuclear cell infiltration correlated well with the degree of interface and lobular hepatitis in PBC, but to a lesser degree in AIH. CD20+ cells were mainly found in the portal tracts and, occasionally, at the interface in both diseases. Elevated AST correlated well with the hepatocyte necroinflammation and mononuclear cell infiltration, specifically CD38+ cells in PBC. No correlation existed between autoantibodies and inflammatory cell infiltration in PBC or AIH. While most AIH cases were IgG-predominant at the interface, PBC cases were divided into IgM-predominant, IgM/IgGequal, and IgG-predominant types, with the latter sharing several features with AIH. CONCLUSION: These results suggest that the hepatocellular injuries associated with interface and lobular hepatitis in AIH and PBC with interface hepatitis may not be identical. © 2014 Baishideng Publishing Group Co., Limited. All rights reserved.", "subitem_description_type": "Abstract"}]}, "item_4_description_5": {"attribute_name": "提供者所属", "attribute_value_mlt": [{"subitem_description": "金沢大学医薬保健研究域医学系", "subitem_description_type": "Other"}]}, "item_4_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.24517/00061729", "subitem_identifier_reg_type": "JaLC"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Baishideng Publishing Group Co"}]}, "item_4_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.3748/wjg.v20.i13.3597", "subitem_relation_type_select": "DOI"}}]}, "item_4_relation_28": {"attribute_name": "関連URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "https://www.wjgnet.com/"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.wjgnet.com/", "subitem_relation_type_select": "URI"}}, {"subitem_relation_name": [{"subitem_relation_name_text": "https://www.wjgnet.com/1007-9327/index.htm"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.wjgnet.com/1007-9327/index.htm", "subitem_relation_type_select": "URI"}}]}, "item_4_rights_23": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright ©The Author(s). 2014 Published by Baishideng Publishing Group Inc. All rights reserved."}]}, "item_4_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AA12048247", "subitem_source_identifier_type": "NCID"}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1007-9327", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kobayashi, Mio"}], "nameIdentifiers": [{"nameIdentifier": "97271", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kakuda, Yuko"}], "nameIdentifiers": [{"nameIdentifier": "22121", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Harada, Kenichi"}], "nameIdentifiers": 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"Lobular hepatitis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Plasma cell subclass", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Primary biliary cirrhosis", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Clinicopathological study of primary biliary cirrhosis with interface hepatitis compared to autoimmune hepatitis", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Clinicopathological study of primary biliary cirrhosis with interface hepatitis compared to autoimmune hepatitis"}]}, "item_type_id": "4", "owner": "18", "path": ["1134"], "permalink_uri": "https://doi.org/10.24517/00061729", "pubdate": {"attribute_name": "公開日", "attribute_value": 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