@article{oai:kanazawa-u.repo.nii.ac.jp:00055455, author = {岡崎, 充善 and 牧野, 勇 and 北川, 裕久 and 中沼, 伸一 and 林, 泰寛 and 中川原, 寿俊 and 宮下, 知治 and 田島, 秀浩 and 高村, 博之 and 太田, 哲生 and Okazaki, Mitsuyoshi and Makino, Isamu and Kitagawa, Hirohisa and Nakanuma, Shinichi and Hayashi, Hironori and Nakagawara, Hisatoshi and Miyashita, Tomoharu and Tajima, Hidehiro and Takamura, Hiroyuki and Ohta, Tetsuo}, issue = {3}, journal = {World Journal of Gastroenterology}, month = {}, note = {We herein report a case of anaplastic carcinoma of the pancreas with remarkable intraductal tumor growth into the main pancreatic duct. A 76-year-old male was referred to our hospital for treatment of a pancreatic tumor. Preoperative examinations revealed a poorly defined tumor in the main pancreatic duct in the body of the pancreas, accompanied with severe dilatation of the main pancreatic duct, which was diagnosed as an intraductal papillary-mucinous neoplasm. We performed distal pancreatectomy and splenectomy. The pathological examination revealed that the tumor consisted of a mixture of anaplastic carcinoma (giant cell type) and adenocarcinoma in the pancreas. There was a papillary projecting tumor composed of anaplastic carcinoma in the dilated main pancreatic duct. The patient is now receiving chemotherapy because liver metastasis was detected 12 mo after surgery. In this case, we could observe a remarkable intraductal tumor growth into the main pancreatic duct. We also discuss the pathogenesis and characteristics of this rare tumor with specific tumor growth. © 2014 Baishideng Publishing Group Co., Limited. All rights reserved., 金沢大学医薬保健研究域医学系}, pages = {852--856}, title = {A case report of anaplastic carcinoma of the pancreas with remarkable intraductal tumor growth into the main pancreatic duct}, volume = {20}, year = {2014} }