{"created":"2023-07-27T06:58:34.218743+00:00","id":57192,"links":{},"metadata":{"_buckets":{"deposit":"8da0094c-b8ee-4e94-82f9-9c8237d33794"},"_deposit":{"created_by":18,"id":"57192","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"57192"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00057192","sets":["2812:2813:2829"]},"author_link":["17606","53548"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-07-10","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"2p.","bibliographicVolumeNumber":"2002 – 2004","bibliographic_titles":[{"bibliographic_title":"平成16(2004)年度 科学研究費補助金 基盤研究(B) 研究成果報告書概要"},{"bibliographic_title":"2004 Fiscal Year Final Research Report Summary","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"表記研究課題のもとに金沢大学・神奈川工科大学・総合研究大学院大学さらには海外研究者の協力を得て共同研究を推し進めてきた。金沢大学においては、ノズルジェットフーリェ変換マイクロ波分光器(FTMW)を新たに構築し、また、神奈川工科大学では既設のFTMW装置の機能拡張を計り、ペプチド分子など生体機能を解明するのに有用と考えられる分子種をとりあげ、純回転スペクトルの測定・解析から、その内部運動に関する情報を得ることに鋭意努め、情報伝達の機構解明の糸口をつかむべく研究を進めてきた。\n当該研究機関中(平成14-16年度)に取りくんだ分子種はdimethyl methyl phosphonate, N-methylpropion amide,1,1-dimethylsilacyclobutane, N-methyl acetamide, N-methylaniline, N,N-dimethylacetamide, Ar-dimethylether, Ne-dimethyletherなどである。いずれもメチル基内部回転運動を含む複数の大振幅内部運動を有するものであり、今回の研究を通してこれら内部運動に関する詳しい情報が得られた。ことに各内部運動間の相互作用に関する知見は情報伝達機構と直接深く関連するものと考えられ、有用な情報といえよう。たとえば、N,N-dimethylacetamideでは、コリオリ相互作用項を通して3個のメチル基を内部回転が伝播する遷移確率、また、1,1-dimethylsilacyclobutaneでは内部回転-リングパッカリング間の相互作用の回転定数への寄与、等々の精密な情報が得られており、実験データの解析を通して得られたこれらの知見は情報伝達機構を考える上で貴重な成果と云えよう。","subitem_description_type":"Abstract"},{"subitem_description":"In the present project, a nozzle-jet Fourier transform microwave (ETTMW) spectrometer was newly constructed in Kanazawa University, and the FTMW existing already in Kanagawa Institute of Technology was revised. Using these two FTMW spectrometers, and also using the instrument in National Institute of Standards and Technology (NIST) of U.S,A. through collaborative work, pure rotational spectra of peptide molecules and other molecular species involving large-amplitude motions were investigated to obtain information on intra-moleculaar interactions useful for understanding mechanism of biological information transmittance. Molecular species studied in the present project are dimethyl methylphosphonate, N-methylpropionamide, N-methylformamide, N-methylacetamide, 1,1-dimethylsilacyclobutane, N-methylaniline, N,N-dimethylacetamide, Ar-dimethyl ether complex, Ne-dimethyl ether complex etc. For examples, a transition probability relating to transmittanee of the three CH_3-internal rotations occurring through Coriolis interaction between overall-rotation and internal-rotation was obtained for the N,N-dimethylacetamide, and a contribution to a rotational constant of the interaction between CH_3-internal rotation and ring-puckering motion was determined for the 1,1-dimethylsilacyclobutane molecule. Information involved in these quantities is useful, which are considered to be strongly related to information transmittance of fiologically related molecules.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:14340177, 研究期間(年度):2002 – 2004","subitem_description_type":"Other"},{"subitem_description":"出典：「高分解能分子分光学的手法を活用した生体機能とくに情報伝達の機構の解明」研究成果報告書　課題番号14340177\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-14340177/143401772004kenkyu_seika_hokoku_gaiyo/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学自然科学研究科","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00063462","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=40019493"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=40019493","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-14340177/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-14340177/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-14340177/143401772004kenkyu_seika_hokoku_gaiyo/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-14340177/143401772004kenkyu_seika_hokoku_gaiyo/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-11-05"}],"displaytype":"detail","filename":"SC-PR-OHASHI-N-kaken 2006-2p.pdf","filesize":[{"value":"97.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"SC-PR-OHASHI-N-kaken 2006-2p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/57192/files/SC-PR-OHASHI-N-kaken 2006-2p.pdf"},"version_id":"dc0ee182-3c6d-48c0-a17b-66a09cc53c01"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"高分解能分子分光学的手法を活用した生体機能とくに情報伝達の機構の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"高分解能分子分光学的手法を活用した生体機能とくに情報伝達の機構の解明"},{"subitem_title":"Study on biological mechanism, specially, information transmittance by malting use of high resolution spectroscopic method","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2829"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-11-05"},"publish_date":"2021-11-05","publish_status":"0","recid":"57192","relation_version_is_last":true,"title":["高分解能分子分光学的手法を活用した生体機能とくに情報伝達の機構の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T14:26:39.821692+00:00"}