@article{oai:kanazawa-u.repo.nii.ac.jp:00058445,
 author = {菅, 拓也 and 宇梶, 裕 and Suga, Takuya and Takahashi, Yuuki and Miki, Chinatsu and Ukaji, Yutaka},
 journal = {Angewandte Chemie International Edition},
 month = {Jan},
 note = {Low-valent Ti-mediated homolytic C–O bond cleavage offers unified access to carbon radicals from ubiquitous non-activated tertiary, secondary, and even primary alcohols. In contrast to the representative Ti reagents, which were ineffective for this purpose, "TiCl 2 (cat)"/Zn (cat = catecholate) was found to be specifically active. This method was applied to the addition reactions of radicals to alkenes and exhibited high generality and yields. More than 50 combinations were examined. The excellent cost-efficiency and accessibility of "TiCl 2 (cat)"/Zn further enhance its applicability. Control experiments proved the presence of a carbon radical intermediate and excluded the pathway via alkyl chlorides. Further mechanistic study indicated that the 1:2 complex of alkoxide (R–O – ) and Ti(III) is an active species in the C–O cleavage., 金沢大学理工研究域物質化学系},
 title = {Direct and Unified Access to Carbon Radicals from Aliphatic Alcohols by Cost-Efficient Titanium-Mediated Homolytic C-OH Bond Cleavage},
 year = {2022}
}