@article{oai:kanazawa-u.repo.nii.ac.jp:00058947,
 author = {小ノ澤, 真一 and 染矢, 富士子 and 塗谷, 栄治 and Onozawa, Shinichi and Someya, Fujiko and Nuriya, Eiji},
 issue = {2},
 journal = {Journal of wellness and health care, Journal of wellness and health care},
 month = {Feb},
 note = {Background: Lung compliance is a parameter of lung expansion. In patients on
ventilator management, it affects ventilatory status and mortality. There are few studies
on permanent ventilator dependence (PVD), a condition defined as when a patient has
been on ventilator management for more than three months. We aimed to clarify the
longitudinal factors affecting lung compliance during the chronic period in PVD subjects.
Methods: A follow-up study was performed on 24 PVD subjects who had been on
ventilator management for approximately 6 years. Static (Cst) and dynamic (Cdyn) lung
compliance and alveolar-arterial PO2 difference (P(A-a)O2) were assessed twice between
2019 and 2020, and the before and after results were compared for each assessment. We
examined the correlation of changes in Cst and Cdyn over time with BMI, age, duration of
ventilation dependence, and the incidence of pneumonia. The subjects were divided into
two groups according to the presence of atelectasis, and changes in Cst, Cdyn, and P(A-a)
O2 were compared between the two groups.
Results: There were no significant changes in lung compliance between the two
measurements in the follow-up. However, at the individual level, a decrease in BMI
inhibited the decrease in Cst. There was no relationship between differences in Cst or
Cdyn and P(A-a)O2, age, ventilator management days, or the incidence of pneumonia.
Differences in P(A-a)O2 were not observed between the two groups divided according to
the presence of atelectasis.
Conclusions: Increased BMI affected lung compliance in PVD subjects during the chronic
period. Regarding atelectasis, its relationship with differences in Cst and Cdyn was not
clear, and impaired lung compliance was considered to resolve after several years of PVD.},
 pages = {1--9},
 title = {Factors associated with decreased lung compliance in subjects with permanent ventilation dependence:A follow-up study},
 volume = {45},
 year = {2022}
}