{"created":"2023-07-27T06:59:23.665020+00:00","id":58959,"links":{},"metadata":{"_buckets":{"deposit":"af59d650-452e-445d-8922-dcf3217e3ba6"},"_deposit":{"created_by":18,"id":"58959","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"58959"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00058959","sets":["4200:1874:1875"]},"author_link":["43","20080","91488","17754","20737","22446","14708","85011","20090","44095","20341","28557"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1985","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"363","bibliographicPageStart":"359","bibliographicVolumeNumber":"34","bibliographic_titles":[{"bibliographic_title":"Radioisotopes"}]}]},"item_4_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Mori, Hirofumi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Shiba, Kazuhiro"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Tsuji, Shiro"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Matsuda, Hiroshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Hisada, Kinichi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kojima, Kazuhiko"}],"nameIdentifiers":[{},{}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ラット脳の3H-スピロペリドールによる受容体マクロオートラジオグラフィに関して, 基礎的検討, すなわちインキュベーション時間, 洗浄時間, 飽和実験, 作動薬, 拮抗薬による抑制効果について検討するとともに, ビデオカメラとコンピュータを組合せたVideo Digitizer Systemを用いてサブトラクションイメージを作成した。その結果, 本法はドーパミン等の受容体の形態学的分布ならびに動態の解析が可能であり, 神経精神疾患の病態解明ならびに陽電子, あるいは単光子横断断層イメージの解釈に有用と期待された。","subitem_description_type":"Abstract"},{"subitem_description":"The kinetic and pharmacological characteristics of 3H-spiroperidol binding sites were studied in slide mounted sections of rat forebrain, and optical binding conditions were defined. Using the receptor macroautoradiographic techniques with tritium-sensitive LKB sheet film, the distribution of dopamine (D2) receptor was determined in slices including striatum of rat brain. The autoradiograms were analyzed using Video Digitizer System combined with video camera and minicomputer, and the subtraction images were obtained.\nThese studies suggest that this quantitative receptor macroautoradiography might be useful in the explanation of etiology in the field of neuro psychiatric diseases and the fundamental studies of positron emission computed tomography, since this method has several advantages over in vivo autoradiography and in vitro receptor assay.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学疾患モデル総合研究センター","subitem_description_type":"Other"}]},"item_4_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00065221","subitem_identifier_reg_type":"JaLC"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本アイソトープ協会 Japan Radioisotope Association"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3769/radioisotopes.34.7_359","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://www.jstage.jst.go.jp/browse/radioisotopes/-char/ja/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/browse/radioisotopes/-char/ja/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"http://www.jrias.or.jp/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jrias.or.jp/","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright ©日本アイソトープ協会 Japan Radioisotope Association"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00351589","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0033-8303","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"1884-4111","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"森, 厚文"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"柴, 和弘"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"辻, 志郎"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"松田, 博史"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"久田, 欣一"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"小島, 一彦"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-21"}],"displaytype":"detail","filename":"ME-PR-SHIBA-K-34_359.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-SHIBA-K-34_359.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/58959/files/ME-PR-SHIBA-K-34_359.pdf"},"version_id":"1530cd69-968d-4621-9a42-4420d467d47d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ラット脳における3H-スピロペリドールによる受容体マクロオートラジオグラフィ","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ラット脳における3H-スピロペリドールによる受容体マクロオートラジオグラフィ"},{"subitem_title":"Receptor macroautoradiography of 3H-spiroperidol binding in rat brain","subitem_title_language":"en"}]},"item_type_id":"4","owner":"18","path":["1875"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-21"},"publish_date":"2022-02-21","publish_status":"0","recid":"58959","relation_version_is_last":true,"title":["ラット脳における3H-スピロペリドールによる受容体マクロオートラジオグラフィ"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T10:17:35.115209+00:00"}