{"created":"2023-07-27T06:59:40.330934+00:00","id":59331,"links":{},"metadata":{"_buckets":{"deposit":"4e9831c4-7ef9-4de0-9e2a-3aa505f657ee"},"_deposit":{"created_by":18,"id":"59331","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"59331"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00059331","sets":["2812:2813:4085"]},"author_link":["15118","97926"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-08-30","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"2p.","bibliographicVolumeNumber":"2021-04-01 – 2022-03-31","bibliographic_titles":[{"bibliographic_title":"令和3(2021)年度 科学研究費補助金 奨励研究 研究概要"},{"bibliographic_title":"2021 Research Project Summary","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Wei, Weilin"}],"nameIdentifiers":[{"nameIdentifier":"15118","nameIdentifierScheme":"WEKO"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"AFM探針先端に三脚型の有機合成分子を結合させ、ケモセレクテイブなライゲーションを用いてタンパク質結合型のAFM探針の開発を行う。修飾したAFM探針を応用し、二つの展望が考えられる。1.従来のAFM探針より自由度があり、多様な分野へ拡張できる。2.修飾した探針が特異的であり、タンパク質とその酵素のように相互作用するため、試料中の不純物から検出された信号と区別しやすく、解析もしやすくなる。また、フリーペプチド先端のあるAFM探針を用いて分子シャペロン試料を観察し、タンパク質のフォールテイング過程を分析することで、生命科学分野におけるタンパク質のダイナミックな挙動に関する新たな知見が期待される。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:21H04127, 研究期間:2021-04-01 – 2022-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「AFM探針の化学修飾を基盤とする生命科学への展開」課題番号21H04127（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n （https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21H04127/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学ナノ生命科学研究所","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00065593","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=21H04127"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=21H04127","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21H04127/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21H04127/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"魏, 威凛"}],"nameIdentifiers":[{"nameIdentifier":"97926","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-18"}],"displaytype":"detail","filename":"FR-PR-WEI-W-kaken 2021-2p.pdf","filesize":[{"value":"107.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"FR-PR-WEI-W-kaken 2021-2p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/59331/files/FR-PR-WEI-W-kaken 2021-2p.pdf"},"version_id":"323be0c5-5d9f-4e94-a22c-206d1bdb8760"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"AFM探針の化学修飾を基盤とする生命科学への展開","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"AFM探針の化学修飾を基盤とする生命科学への展開"}]},"item_type_id":"9","owner":"18","path":["4085"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-03-18"},"publish_date":"2022-03-18","publish_status":"0","recid":"59331","relation_version_is_last":true,"title":["AFM探針の化学修飾を基盤とする生命科学への展開"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-07-01T05:17:04.739303+00:00"}