{"created":"2023-07-27T07:00:19.626388+00:00","id":60209,"links":{},"metadata":{"_buckets":{"deposit":"3d6c2363-773e-44b1-88b1-35a4c9298ac2"},"_deposit":{"created_by":18,"id":"60209","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"60209"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00060209","sets":["2812:2813:2838"]},"author_link":["27765","27759"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-04-21","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"2p.","bibliographicVolumeNumber":"1994","bibliographic_titles":[{"bibliographic_title":"平成7(1995)年度 科学研究費補助金 一般研究(C) 研究課題概要"},{"bibliographic_title":"1995 Research Project Summary","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"1.申請者が開発したプロトベルベリンからの生合成的変換によるベンゾフェナンスリジン合成法の反応条件を検討し、一般的合成条件を確立した。\n2.各種のo‐スチリル安息香酸誘導体から、ベンゾキノン存在下5mol%のPdCl_2(CH_3CN)_2を用いる触媒的アシロキシパラデーション法を開発して、3‐アリールイソクマリンの一般合成法を開発した。\n3.上記の反応を活用して、抗腫瘍性ベンゾフェナンスリジンアルカロイドnitidineのイソクマリン体を経由する新しい合成法を開拓した。\n4.Meldrum酸を利用し、4‐arylquinolinequinoneを経由して、抗腫瘍性海洋産アルカロイドの基本骨格である4‐oxo‐4H‐pyrido[2,3,4‐kl]acridineの新規合成に成功した。\n5.上記ルートに従って、4環性抗腫瘍性海洋産アルカロイドのcystodytin類の共通合成中間体である6‐(2‐aminoethyl)‐4‐oxo‐4H‐pyrido[2,3,4‐kl]acridine体の合成に成功した。今後、cystodytin類並びに関連海洋産アルカロイドの全合成を完成させる予定である。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:06672094, 研究期間(年度):1994","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「抗腫瘍性含窒素多環状化合物の合成」課題番号06672094\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-06672094/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学薬学部","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00066460","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=80028844"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=80028844","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-06672094/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-06672094/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-06-16"}],"displaytype":"detail","filename":"PH-PR-HANAOKA-M-kaken 2016-2p.pdf","filesize":[{"value":"123.8 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"PH-PR-HANAOKA-M-kaken 2016-2p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/60209/files/PH-PR-HANAOKA-M-kaken 2016-2p.pdf"},"version_id":"4438a2b6-9dfd-4f34-a031-e008e31e31db"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"抗腫瘍性含窒素多環状化合物の合成","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"抗腫瘍性含窒素多環状化合物の合成"}]},"item_type_id":"9","owner":"18","path":["2838"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-06-16"},"publish_date":"2022-06-16","publish_status":"0","recid":"60209","relation_version_is_last":true,"title":["抗腫瘍性含窒素多環状化合物の合成"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:51:59.727701+00:00"}