{"created":"2023-07-27T07:00:28.557447+00:00","id":60419,"links":{},"metadata":{"_buckets":{"deposit":"1213712f-e9aa-48a6-bd7b-cb301dced573"},"_deposit":{"created_by":18,"id":"60419","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"60419"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00060419","sets":["2812:2813:2838"]},"author_link":["22029"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1997-03-03","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"3p.","bibliographicVolumeNumber":"1993 – 1995","bibliographic_titles":[{"bibliographic_title":"平成7(1995)年度 科学研究費補助金 試験研究(B) 研究成果報告書概要"},{"bibliographic_title":"1995 Fiscal Year Final Research Report Summary","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"小動物の行動性体温調節と自律性体温調節の関わり合いを理解するため、ラットなどが自由にその至適環境温度を選ぶことの出来る小動物用温度勾配装置・サーモクリン・を試作した。このサーモクリンは、内寸200×16×18(H)cmで、両端に溶接した銅製パイプにそれぞれ独立して冷水と温水を循環させ、装置内に長軸に沿って約8℃から約45℃の温度勾配を持たせた飼育実験装置であり、その中にラットを入れて複数日にわたって連続的に、ラットの居る位置の環境温度(至適環境温度)、行動量、体温その他の自律機能を以下の各種の条件下で測定した。1.発熱時の行動性体温調節と日内変動。体温は夜間に高く昼間に低いが至適環境温度はその逆であった。夜間、ラットは発熱物質の投与で体温が上昇する直前に高い至適環境温度を、また解熱の前に低い至適環境温度を選択した。2.暑熱耐性ラットの体温調節行動。普通のラットに比しFOXラットの体温と至適環境温度は低かった。FOXラットでは、それぞれの体温調節反応が昴進する低および高閾値環境温のいずれも低くなった。3.エンドトキシンショック。大量の発熱物質投与で体温は逆に下降し至適環境温度も同様に下降した。4.摂食後の行動性体温調節反応。摂食直後には体温の上昇に伴って低い至適環境温度を選択したが、体温の回復とともに旧に復した。5.ケージスイッチテストの機序。実験環境にナイーブなラットでは、少なくとも3日間は高い体温とともに高い至適温度を選択した。6.ストレス負荷。拘束によるストレス負荷ラットでは、体温が高く、体温調節反応の閾値温度は高温側に移動した。7.運動鍛練ラットの体温調節反応。このラットでは常に非蒸発性の熱放散反応が昴進した。","subitem_description_type":"Abstract"},{"subitem_description":"The purpose of this study was to design a thermocline for accurate measurements of preferred ambient temperature of small animals such as rats in various conditions. The dimensions of the thermocline were 200 x 16 x 18 (H) cm, whose both ends were welded with cupper tubings in which cold and hot water was independently circulated and a thermal, gradient was maintained along the axis of the thermocline. With this instrument the preferred temperature of rats was estimated. Body temperature was continuously measured by telemetry. 1) Behavioral thermoregulation and its diurnal change during fever. The preferred temperature was higher in the inactive phase and lower in the active phase. After a pyrogen was injected the preferred temperature rose before the riso of body temperature and fell before the thermolysis began. 2) Behavioral thermoregulation in FOK rats. Body and preferred temperatures were always lower in FOK rats. The critical temperatures for the increase in metabolic rate and for the skin vasodilatation were also lower. 3) Endotoxin shock. A large dose of endotoxin caused a fall in body temperature as well as the preferred temperature. 4) Behavioral thermoregulation after feeding. Shortly after feeding the rats selected a lower ambient temperature. 5) In the rats naive to the experimental condition maintained higher body and preferred temperatures for at least 3 days. 6) Effects of restraint and exercise. During restraint, the rats maintained higher body temperature and the critical temperatures for thermoregulatory responses. In exercise-trained rats nonevaporative heat loss was always higher than control rats.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:05557005, 研究期間(年度):1993 – 1995","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「行動性体温調節機構の解析を目的とした小動物用温度勾配装置の試作研究」課題番号05557005\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-05557005/055570051995kenkyu_seika_hokoku_gaiyo/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医学部","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00066667","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=80023646"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=80023646","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-05557005/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-05557005/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-05557005/055570051995kenkyu_seika_hokoku_gaiyo/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-05557005/055570051995kenkyu_seika_hokoku_gaiyo/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-07-08"}],"displaytype":"detail","filename":"ME-PR-NAGASAKA-T-kaken 1997-3p.pdf","filesize":[{"value":"105.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-NAGASAKA-T-kaken 1997-3p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/60419/files/ME-PR-NAGASAKA-T-kaken 1997-3p.pdf"},"version_id":"bd69facd-0b93-414e-ac6e-2aa0ff0c0bec"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"行動性体温調節機構の解析を目的とした小動物用温度勾配装置の試作研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"行動性体温調節機構の解析を目的とした小動物用温度勾配装置の試作研究"},{"subitem_title":"Thermocline for the study of behavioral thermoregulation in small animals","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2838"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-07-08"},"publish_date":"2022-07-08","publish_status":"0","recid":"60419","relation_version_is_last":true,"title":["行動性体温調節機構の解析を目的とした小動物用温度勾配装置の試作研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:39:35.658483+00:00"}