@article{oai:kanazawa-u.repo.nii.ac.jp:00062147, author = {菅, 拓也 and 添田, 貴宏 and 宇梶, 裕 and Hasegawa, Megumi and Suga, Takuya and Soeta, Takahiro and Ukaji, Yutaka}, issue = {17}, journal = {Journal of Organic Chemistry}, month = {Sep}, note = {A unique and efficient formation of 3,6-dihydro-2H-1,2-oxazines starting from α,β-unsaturated nitrones has been achieved. The nucleophilic addition of dimethylsulfoxonium methylide to the C═N bond of an α,β-unsaturated nitrone to form an aziridine N-oxide followed by the Meisenheimer rearrangement affords 3,6-dihydro-2H-1,2-oxazine in up to 70% yield. Methylene was confirmed to be incorporated at the C3 position of the ring. A wide range of β-aryl-substituted α,β-unsaturated nitrones were applicable to this reaction., Embargo Period 12 months, 金沢大学理工学研究域物質化学系}, pages = {11258--11264}, title = {Synthesis of 3,6-Dihydro-2H-1,2-oxazines via Dimethylsulfoxonium Methylide Addition to α,β-Unsaturated Nitrones}, volume = {85}, year = {2020} }