{"created":"2023-07-27T06:25:17.828302+00:00","id":8535,"links":{},"metadata":{"_buckets":{"deposit":"863d0a6d-eacf-4c9f-af2f-4847e8cc2d9a"},"_deposit":{"created_by":3,"id":"8535","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"8535"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00008535","sets":["934:935:936"]},"author_link":["12032","12029","12033","42","1064","10974","11933","12031","12030"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"247","bibliographicPageStart":"237","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Transactions of Japanese Society for Medical and Biological Engineering"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In this preliminary study, we examined in human volunteers the performance of the developed prototype device for non-invasive quantification of blood alcohol concentration (BAC) by near-infrared light which is highly transparent to the body. We aimed at applying the results to the final goal of developing a novel alcohol-based vehicle ignition-interlock device. Accumulating evidence shows that one of the ethyl alcohol absorption peaks in the near-infrared region is present at 1,185 nm. We combined this with our recent development of a non-invasive optical method for blood glucose measurement, which we call pulse glucometry, using blood volume pulsations in a finger within a cardiac cycle. Thus, we developed a novel method, pulse alcometry, for non-invasive measurement of BAC. We calculated second derivative values of optical density (OD λ\") to remove baseline over a band including three wavelengths, 1,150 nm, 1,185 nm, and 1,220 nm. Then, a simple linear regression analysis was performed with the measured OD λ\" to predict BAC levels. In 3 healthy male volunteers, during alcohol intake and washout, periodic optical measurements using the present device were made simultaneously with collection of blood samples for in vitro BAC analysis. In leave-one-out cross validations within an individual, the measured BAC and the predicted BAC correlated well (r = 0.773~0.846, mean absolute error = 0.134~0.333mg/ml). We conclude that, from the results of this preliminary study, the new method appears to be able to estimate BAC levels non-invasively. However, further investigations in a larger group of subjects will be needed in order to determine fully the operational performance of this new measurement system.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Society for Medical and Biological Engineering = 日本生体医工学会 JSMBE"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/40019356725","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.asas.or.jp/jsmbe/","subitem_relation_type_select":"URI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA11633569","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1347-443X","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山越, 健弘"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"小川, 充洋"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"松村, 健太"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"板坂, 優希"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宮崎, 慎平"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山越, 康弘"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Rolfe, Peter"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"廣瀬, 元"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山越, 憲一"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"TE-PR-YAMAKOSHI-T-237.pdf","filesize":[{"value":"3.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"TE-PR-YAMAKOSHI-T-237.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/8535/files/TE-PR-YAMAKOSHI-T-237.pdf"},"version_id":"c28ef367-d03a-4299-9195-9c2efd65b5f1"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"光電容積脈波式血中アルコール濃度計測装置の開発: in vivo試験による予備的検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"光電容積脈波式血中アルコール濃度計測装置の開発: in vivo試験による予備的検討"},{"subitem_title":"A preliminary study on development of a novel optical instrument for non-invasive blood alcohol measurement: Proposal of pulse alcometry","subitem_title_language":"en"}]},"item_type_id":"4","owner":"3","path":["936"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"8535","relation_version_is_last":true,"title":["光電容積脈波式血中アルコール濃度計測装置の開発: in vivo試験による予備的検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T02:08:20.178847+00:00"}