WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "9a1cb9f0-86d8-4af3-a9b8-91d764ba1c4c"}, "_deposit": {"created_by": 3, "id": "13004", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "13004"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00013004", "sets": ["1134"]}, "author_link": ["593", "20109", "20323", "20324", "20326", "20325", "209"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2004-02-20", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "85", "bibliographicPageStart": "76", "bibliographicVolumeNumber": "31", "bibliographic_titles": [{"bibliographic_title": "理学療法学"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "関節固定後の拘細の治療手段としてストレッチが関節構成体に及ぼす影響を観察する目的で研究を行った。対象は9週齢のWistar系雄ラット16匹(正常群,拘細群,非治療群,治療群それぞれ4匹)を用いた。正常群は2週間通常飼育を行った。拘縮部は膝関節最大屈曲位で2週間ギプス固定して飼育した。非治療群は,拘細作製後,ギプス除去し2週間通常飼育した。治療部では,拘細作製後,ストレッチを2週間施行した。ラットは安楽死後,膝関節とハムストリングスを採取し,組織に対してヘマトキシリン・エオジン染色を行った。組織の観察は,滑膜組織,滑膜軟骨移行部,関節包後部,ハムストリングス中央部で行った。結果,拘細部では滑脱細胞の萎縮と増殖,関節包の密性化,筋線維束間の狭小化が起こっていた。この変化が,治療群では正常群に近い状態へ回復傾向を示しており,非治療群では治療群ほどの回復は見られなかった。このことからストレッチは固定によって生じた関節拘細の治療として有効な手段である事が示唆された。 To obtain the histopathological findings for contracture mechanism and clarify the effect of stretching, we conducted experiments to observe the histopathological changes in joint components after knee joint immobility in rats. Sixteen adult, nine-week-old male Wistar rats (body weight: 260 g-285 g) were used for this study. The four rats of the control group were raised normally for two weeks. The other 12 rats had their right knee joints immobilized with a cast fixator for two weeks. The four rats of the contracture group were euthanatized immediately after contracture had been achieved. The four rats of the stretch group were subjected to stretching of the immobilized knee for two weeks. The four rats of the non-stretch group were not subjected to stretching. Stretching consisted of five cycles of 50-second stretching and a 10-second rest. The trunk of the rats of the stretch group was immobilized, and the ankle was stretched in the caudal direction. The knee joints excised after sacrifice were fixed in formalin, decalcified and embedded in paraffin. Staining was done with hematoxylin and examination was by a light microscope. Atrophy of synoviocytes, fibrosis of the layer underlying the synovium, dilatation, proliferation of the synovium at the cartilage-synovium migration area and congestion of the microvasculature were observed in the contracture group. The stretch group returned to almost normal conditions, but the non-stretch group to a lesser extent. The fibroconnective tissue of the contracture group was denser than that of any other group, and the stretch group improved more than the nonstretch group. However, fibrosis of the stretch group was denser than that of the control group. The surface layer of the articular cartilage in the contracture group showed fibrous proliferation in contrast to that of the control group. The contracture group showed thinner connective tissue between the muscle fibers than any other group. The stretch group improved more than the nonstretch group; on the other hand the connective tissue of the stretch group was thinner than that of the control group. Histopathological changes in the joint components showing contracture were considered to be secondary disorders caused by the cast fixation in this study. However, the stretch group improved more than the non-stretch group, suggesting that stretching has a beneficial effect on joint contracture.", "subitem_description_type": "Abstract"}]}, "item_4_description_5": {"attribute_name": "提供者所属", "attribute_value_mlt": [{"subitem_description": "金沢大学大学院医学系研究科機能障害学", "subitem_description_type": "Other"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "日本理学療法士協会"}]}, "item_4_relation_28": {"attribute_name": "関連URI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "http://ci.nii.ac.jp/naid/110003994136/", "subitem_relation_type_select": "URI"}}]}, "item_4_rights_23": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "本文データは日本理学療法士協会の許諾に基づきCiNiiから複製したものである"}]}, "item_4_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11545224", "subitem_source_identifier_type": "NCID"}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0289-3770", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "武村, 啓住"}], "nameIdentifiers": [{"nameIdentifier": "20323", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70303287", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=70303287"}, {"nameIdentifier": "70303287", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000070303287"}]}, {"creatorNames": [{"creatorName": "細, 正博"}], "nameIdentifiers": [{"nameIdentifier": "209", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "20219182", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=20219182"}, {"nameIdentifier": "20219182", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=20219182"}, {"nameIdentifier": "20219182", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000020219182"}]}, {"creatorNames": [{"creatorName": "由久保, 弘明"}], "nameIdentifiers": [{"nameIdentifier": "20324", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "松崎, 太郎"}], "nameIdentifiers": [{"nameIdentifier": "593", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "10401910", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10401910"}, {"nameIdentifier": "10401910", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=10401910"}, {"nameIdentifier": "10401910", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000010401910"}]}, {"creatorNames": [{"creatorName": "小島, 聖"}], "nameIdentifiers": [{"nameIdentifier": "20325", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "渡邊, 晶規"}], "nameIdentifiers": [{"nameIdentifier": "20326", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "立野, 勝彦"}], "nameIdentifiers": [{"nameIdentifier": "20109", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "40092788", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=40092788"}, {"nameIdentifier": "40092788", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000040092788"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-10-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ME-PR-HOSO-M-76.pdf", "filesize": [{"value": "4.7 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 4700000.0, "url": {"label": "ME-PR-HOSO-M-76.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/13004/files/ME-PR-HOSO-M-76.pdf"}, "version_id": "48a0c7fe-5e26-4e9c-b3de-ab3b3e593c2f"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "ラット拘細膝", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ストレッチ 病理組織", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "ラット膝関節2週固定後の拘縮に対するストレッチが関節構成体に及ぼす病理組織学的影響(2002年度研究助成論文)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "ラット膝関節2週固定後の拘縮に対するストレッチが関節構成体に及ぼす病理組織学的影響(2002年度研究助成論文)"}, {"subitem_title": "Histopathological Effects of the Stretching on Joint Components after Two-week Knee Joint Immobilization in Rats(Articles Supported by Grants from JPTA)", "subitem_title_language": "en"}]}, "item_type_id": "4", "owner": "3", "path": ["1134"], "permalink_uri": "http://hdl.handle.net/2297/7333", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-10-03"}, "publish_date": "2017-10-03", "publish_status": "0", "recid": "13004", "relation": {}, "relation_version_is_last": true, "title": ["ラット膝関節2週固定後の拘縮に対するストレッチが関節構成体に及ぼす病理組織学的影響(2002年度研究助成論文)"], "weko_shared_id": -1}
ラット膝関節2週固定後の拘縮に対するストレッチが関節構成体に及ぼす病理組織学的影響(2002年度研究助成論文)
http://hdl.handle.net/2297/7333
http://hdl.handle.net/2297/733314b6fc78-b997-43cd-8a48-bbdd6f3dad79
名前 / ファイル | ライセンス | アクション |
---|---|---|
ME-PR-HOSO-M-76.pdf (4.7 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | ラット膝関節2週固定後の拘縮に対するストレッチが関節構成体に及ぼす病理組織学的影響(2002年度研究助成論文) | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Histopathological Effects of the Stretching on Joint Components after Two-week Knee Joint Immobilization in Rats(Articles Supported by Grants from JPTA) | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
武村, 啓住
× 武村, 啓住× 細, 正博× 由久保, 弘明× 松崎, 太郎× 小島, 聖× 渡邊, 晶規× 立野, 勝彦 |
|||||
提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学大学院医学系研究科機能障害学 | |||||
書誌情報 |
理学療法学 巻 31, 号 1, p. 76-85, 発行日 2004-02-20 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0289-3770 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11545224 | |||||
出版者 | ||||||
出版者 | 日本理学療法士協会 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 関節固定後の拘細の治療手段としてストレッチが関節構成体に及ぼす影響を観察する目的で研究を行った。対象は9週齢のWistar系雄ラット16匹(正常群,拘細群,非治療群,治療群それぞれ4匹)を用いた。正常群は2週間通常飼育を行った。拘縮部は膝関節最大屈曲位で2週間ギプス固定して飼育した。非治療群は,拘細作製後,ギプス除去し2週間通常飼育した。治療部では,拘細作製後,ストレッチを2週間施行した。ラットは安楽死後,膝関節とハムストリングスを採取し,組織に対してヘマトキシリン・エオジン染色を行った。組織の観察は,滑膜組織,滑膜軟骨移行部,関節包後部,ハムストリングス中央部で行った。結果,拘細部では滑脱細胞の萎縮と増殖,関節包の密性化,筋線維束間の狭小化が起こっていた。この変化が,治療群では正常群に近い状態へ回復傾向を示しており,非治療群では治療群ほどの回復は見られなかった。このことからストレッチは固定によって生じた関節拘細の治療として有効な手段である事が示唆された。 To obtain the histopathological findings for contracture mechanism and clarify the effect of stretching, we conducted experiments to observe the histopathological changes in joint components after knee joint immobility in rats. Sixteen adult, nine-week-old male Wistar rats (body weight: 260 g-285 g) were used for this study. The four rats of the control group were raised normally for two weeks. The other 12 rats had their right knee joints immobilized with a cast fixator for two weeks. The four rats of the contracture group were euthanatized immediately after contracture had been achieved. The four rats of the stretch group were subjected to stretching of the immobilized knee for two weeks. The four rats of the non-stretch group were not subjected to stretching. Stretching consisted of five cycles of 50-second stretching and a 10-second rest. The trunk of the rats of the stretch group was immobilized, and the ankle was stretched in the caudal direction. The knee joints excised after sacrifice were fixed in formalin, decalcified and embedded in paraffin. Staining was done with hematoxylin and examination was by a light microscope. Atrophy of synoviocytes, fibrosis of the layer underlying the synovium, dilatation, proliferation of the synovium at the cartilage-synovium migration area and congestion of the microvasculature were observed in the contracture group. The stretch group returned to almost normal conditions, but the non-stretch group to a lesser extent. The fibroconnective tissue of the contracture group was denser than that of any other group, and the stretch group improved more than the nonstretch group. However, fibrosis of the stretch group was denser than that of the control group. The surface layer of the articular cartilage in the contracture group showed fibrous proliferation in contrast to that of the control group. The contracture group showed thinner connective tissue between the muscle fibers than any other group. The stretch group improved more than the nonstretch group; on the other hand the connective tissue of the stretch group was thinner than that of the control group. Histopathological changes in the joint components showing contracture were considered to be secondary disorders caused by the cast fixation in this study. However, the stretch group improved more than the non-stretch group, suggesting that stretching has a beneficial effect on joint contracture. | |||||
権利 | ||||||
権利情報 | 本文データは日本理学療法士協会の許諾に基づきCiNiiから複製したものである | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://ci.nii.ac.jp/naid/110003994136/ |