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Clinical Perspectives of Genetic Analyses on Dyslipidemia and Coronary Artery Disease.
https://doi.org/10.24517/00014452
https://doi.org/10.24517/00014452d464721c-d0ee-48fa-aad5-d156b58eabbe
名前 / ファイル | ライセンス | アクション |
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ME-PR-YAMAGISHI-M-452.pdf (471.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-05-10 | |||||
タイトル | ||||||
タイトル | Clinical Perspectives of Genetic Analyses on Dyslipidemia and Coronary Artery Disease. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.24517/00014452 | |||||
ID登録タイプ | JaLC | |||||
著者 |
Tada, Hayato
× Tada, Hayato× Kawashiri, Masa-aki× Yamagishi, Masakazu |
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著者別表示 |
多田, 隼人
× 多田, 隼人× 川尻, 剛照× 山岸, 正和 |
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書誌情報 |
Journal of Atherosclerosis and Thrombosis 巻 24, 号 5, p. 452-461, 発行日 2017-05-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1340-3478 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11018976 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.5551/jat.RV17002 | |||||
出版者 | ||||||
出版者 | Japan Atherosclerosis Society = 日本動脈硬化学会 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We have learned that low-density lipoprotein (LDL) cholesterol is the cause of atherosclerosis from various aspects, including a single case with familial hypercholesterolemia, other cases with different types of Mendelian dyslipidemias, large-scale randomized controlled trials using LDL cholesterol lowering therapies, and Mendelian randomization studies using common as well as rare variants associated with LDL cholesterol levels. There is no doubt that determinations of genotypes in lipid-associated genes have contributed not only to the genetic diagnosis for Mendelian dyslipidemias but also to the discoveries of novel therapeutic targets. Furthermore, recent studies have shown that such genetic information could provide useful clues for the risk prediction as well as risk stratification in general and in particular population. We provide the current understanding of genetic analyses relating to plasma lipids and coronary artery disease. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出版者照会後に全文公開 | |||||
権利 | ||||||
権利情報 | Copyright © Japan Atherosclerosis Society 日本動脈硬化学会 (CC-BY NC SA) | 本論文の著作権は日本動脈硬化学会が保持しています | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.j-athero.org/en/index.html | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/browse/jat |