Leaves are acquired independently in pteridophytes and seed plants. This implies that different mechanisms are used for leaf development between these two groups. In this study, we observed expression patterns of some transcription factors in leaf of Certopteris richardii, which are inevitable for leaf development of seed plants. We also conducted RNA-seq analysis to grasp gene expression in leaf of Ceratopteris comprehensively and compared the obtained data with those of seed plants. These data partly suggests that different mechanisms are prevailed in leaves of pteridophytes and seed plants.