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Reversibility of the Pulmonary Function Based on the Partial Flow-volume Curve Predicts the Efficacy of Bronchodilator Therapy for Treating Chronic Cough
http://hdl.handle.net/2297/36474
http://hdl.handle.net/2297/36474bcbc6097-95f9-47a6-b655-e0d3af772917
名前 / ファイル | ライセンス | アクション |
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ME-PR-WADA-T-2017.pdf (599.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Reversibility of the Pulmonary Function Based on the Partial Flow-volume Curve Predicts the Efficacy of Bronchodilator Therapy for Treating Chronic Cough | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Nakade, Yusuke
× Nakade, Yusuke× Fujimura, Masaki× Ohkura, Noriyuki× Nakata, Masako× Nanbu, Yuko× Oe, Hiroyasu× Horita, Hiroshi× Sakai, Yoshio× Wada, Takashi |
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書誌情報 |
Internal Medicine 巻 52, 号 18, p. 2017-2023, 発行日 2013-01-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0918-2918 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10827774 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2169/internalmedicine.52.8604 | |||||
出版者 | ||||||
出版者 | The Japanese Society of Internal Medicine 日本内科学会 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective Partial expiratory flow-volume curves have the potential to detect mild bronchoconstriction because they are not affected by the modulatory effects of deep inspiration. The aim of this study was to investigate the relationship between the efficacy of bronchodilator therapy (BDT) in treating the cough and to assess the increase in the expiratory flow of the partial flow-volume curve at 40% above the residual volume level (PEF40) caused by treatment with a short-acting beta-2 agonist (SABA) in patients with chronic nonproductive cough. Methods We measured the reversibility of PEF40 caused by a SABA in 42 patients with chronic nonproductive cough at visit 1 (day 0). The patients received BDT for six days. The visual analogue scale (VAS) was used to assess the efficacy of BDT in treating coughing at visit 2 (day 7) (0 mm, 'no cough;' 100 mm, 'no change in coughing'). Results Reversibility of the PEF40 was correlated (r=0.690, p<0.001) with the VAS score determined at visit 2 and was higher in the patients with cough variant asthma (CVA) (44.9±18.3%) than in those with atopic cough (13.4±10.4%) (p<0.01). Conclusion Reversibility of the PEF40 predicted the efficacy of BDT in patients with chronic nonproductive cough and helped to identify patients with CVA. | |||||
権利 | ||||||
権利情報 | Copyright © 2013 by The Japanese Society of Internal Medicine 日本内科学会 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
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識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/browse/internalmedicine | |||||
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識別子タイプ | URI | |||||
関連識別子 | http://www.naika.or.jp/ |