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Sensitization to Bjerkandera adusta Enhances Severity of Cough Symptom in Patients with Fungus-Associated Chronic Cough(FACC)
http://hdl.handle.net/2297/30220
http://hdl.handle.net/2297/3022089981d56-83b2-49b4-8ab3-26d9055020ff
名前 / ファイル | ライセンス | アクション |
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ME-PR-FUJIMURA-M-205.pdf (77.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Sensitization to Bjerkandera adusta Enhances Severity of Cough Symptom in Patients with Fungus-Associated Chronic Cough(FACC) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ogawa, Haruhiko
× Ogawa, Haruhiko× Fujimura, Masaki× Takeuchi, Yasuo× Makimura, Kouichi× Satoh, Kazuo |
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書誌情報 |
Medical Mycology Journal 巻 52, 号 3, p. 205-212, 発行日 2011-01-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2185-6486 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12518136 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3314/mmj.52.205 | |||||
出版者 | ||||||
出版者 | 日本医真菌学会Japanese Journal of Medical Mycology | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | [Objective]The aim of the present study was to clarify the influence of sensitization to Bjerkandera adusta(B. adusta)on the clinical manifestation in patients with fungus-associated chronic cough(FACC).[Methods]Seventeen patients with FACC who underwent bronchoprovocation tests using an antigenic solution of B. adusta were selected from among 21 FACC patients. We compared the allergological findings and clinical characteristics of the FACC patients who showed a positive reaction to the bronchoprovocation test(Allergic fungal cough sensitized to B. adusta; AFC-Bj)with the remaining FACC patients(non AFC-Bj)retrospectively.[Results]The eleven patients with AFC-Bj had a median age of 52(range, 22-70)years, and 45.5% were female. The respective values for six patients with non AFC-Bj were 47.5(range, 36-60)years of age, and 33.3% were female. The positive ratios for an immediate cutaneous reaction(45.5%; p<0.05)and the lymphocyte stimulation test(63.6%; p<0.05)to B. adusta were found to be significantly higher in the AFC-Bj group than in the non AFC-Bj group. The total time required for complete remission of cough symptoms was longer(median 20, range 12-43 weeks; p=0.0009), and the recurrence ratio of coughing was more frequent in the AFC-Bj group in comparison to those in non AFC-Bj group(2, range 1-3 times and 0.5, range 0-1 times, respectively).[Conclusions]This study demonstrated that B. adusta, a basidiomycetous is an environmental fungus attracting attention because of its possible role in enhancing the cough severity of FACC patients via the sensitization to this fungus. | |||||
権利 | ||||||
権利情報 | Copyright (c) 2011 日本医真菌学会 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://japanlinkcenter.org/JST.JSTAGE/mmj/52.205 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.jsmm.org/ |