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Scaffold proteins in mammalian MAP kinase cascades
https://doi.org/10.24517/00027530
https://doi.org/10.24517/00027530078cc24f-4dc2-4660-bd4a-a22edf776966
名前 / ファイル | ライセンス | アクション |
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CA-PR-YOSHIOKA-K-657.pdf (213.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-05 | |||||
タイトル | ||||||
タイトル | Scaffold proteins in mammalian MAP kinase cascades | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.24517/00027530 | |||||
ID登録タイプ | JaLC | |||||
著者 |
Yoshioka, Katsuji
× Yoshioka, Katsuji |
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著者別表示 |
善岡, 克次
× 善岡, 克次 |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学がん研究所がん分子細胞制御 | |||||
書誌情報 |
Journal of Biochemistry 巻 135, 号 6, p. 657-661, 発行日 2004-06-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0021-924X | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00694073 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1093/jb/mvh079 | |||||
出版者 | ||||||
出版者 | 日本生化学会 = Japanese Biochemical Society | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The mitogen-activated protein kinase (MAPK) signaling pathway, which is conserved from yeast to humans, is activated in response to a variety of extra- and intracellular stimuli, and plays key roles in multiple cellular processes, including proliferation, differentiation, and apoptosis. The MAPK pathway transmits its signal through the sequential phosphorylation of MAPK kinase kinase to MAPK kinase to MAPK. Specific and efficient activation of the MAPK cascades is crucial for proper cellular responses to stimuli. As shown in yeast, the mammalian MAPK signaling system may also employ scaffold proteins, in part, to organize the MAPK signaling components into functional MAPK modules, thereby enabling the efficient activation of specific MAPK pathways. This review article describes recent advances in the study of potential mammalian scaffold proteins that may help us understand the complex regulation, including the spatial and temporal control, of the mammalian MAPK signaling pathways. | |||||
権利 | ||||||
権利情報 | © 2004 The Japanese Biochemical Society | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | http://dx.doi.org/10.1093/jb/mvh079 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://jb.oxfordjournals.org/cgi/content/abstract/135/6/657 |