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全胚免疫染色と分子生物学的手法による内臓と四肢の神経・血管・筋の形成と再生の解明
https://doi.org/10.24517/00034704
https://doi.org/10.24517/00034704692a843e-4a0c-484a-b470-eda9d7de532b
名前 / ファイル | ライセンス | アクション |
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ME-PR-TANAKA-S-kaken 2008-5p.pdf (174.4 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2017-10-05 | |||||
タイトル | ||||||
タイトル | 全胚免疫染色と分子生物学的手法による内臓と四肢の神経・血管・筋の形成と再生の解明 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Elucidation of three dimension structure of the cardiac nerves and branches and of liver- distributing arteries in the adults and embryos of human and muskrat beavers, using our unique technology and whole mount in situ hybridication | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
ID登録 | ||||||
ID登録 | 10.24517/00034704 | |||||
ID登録タイプ | JaLC | |||||
著者別表示 |
Tanaka, Shigenori
× Tanaka, Shigenori |
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書誌情報 |
平成19(2007)年度 科学研究費補助金 基盤研究(C) 研究成果報告書 en : 2007 Fiscal Year Final Research Report 巻 2006-2007, p. 5p., 発行日 2008-04-01 |
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出版者 | ||||||
出版者 | 金沢大学医学系研究科 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 心臓神経(交感神経由来)の形態解明と膀胱尖・臍・肝鎌状間膜・肝円束内を走行する血管の形態解明研究を推進した。心臓枝は内臓伴行・分布と内臓血管伴行の形態である迷走神経由来であるので、形態解明は難しくない。それに対して、当該の心臓神経は椎骨に接する交感神経幹由来であるので、体壁レベルの広範囲に亘り多数起こるので、神経同士の結合が多く、走行が複雑であるので、心臓枝よりも形態解明は困難である。とりわけ、ヒトの心臓神経は実験脊椎動物よりも形態が大きく、脂肪が多いので形態解明は至難である。我が教室開発の脱脂と神経・血管染色方法にてヒトの心臓神経の形態解明を行い、その成果に依拠して博士課程学生を指導し、ジャコウネズミでの心臓神経の形態解明を行い、Anat.Rec.(Hoboken290,2007)に掲載された。ヒトとジャコウネズミの胆嚢に分布する神経は、World J.Gastroenterol(13,2007)に掲載された。脳細胞遺伝子学の研究者とも連携して、電子顕微鏡での形態解明を行い、Nature(Vol.446,2007)に掲載された。膀胱尖・臍・肝鎌状間膜・肝円束内を走行する血管の形態解明は修士課程の学生を指導し、成果が平成19年度において卒業審査合格となった。上記の教室開発研究方法にて、全実習体において腹壁からの肝臓への血管と尿膜管形態の存在が確認され、論文発表準備中である。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We have elucidated three-dimensional structure of the cardiac nerves which originate from sympathetic nerves and distribute to the heart, coursing cardiac arterial and venous gates, Furthermore, we have endeavored to clarify blood vessels coursing in the floor of urinary bladder ; umbilical fold, and in the farciform et round ligaments of liver. Clarification of vagus nerve branches, including cardiac branches, is not difficult, because these branches course only on or in the internal organs. Thereagainst, these sympathetic nerves originate from the sympathetic nerves never to the vertebral columun. Therefore, the cardiac nerves are very numerousness and complex form. Therefore, three-dimensional clarification of these cardiac nerves is very difficult. Especially, the anatomical area in human bodies is exceedingly large, including adipose. We have developed technology in order to stain nerves and vessels. Using this technology, we have clarified the structure of human cardiac nerves. Acco rding to these results, we have coached a doctoral student. This doctoral student has elucidated three-dimensional structure of nerves and arteries distributing to the heart in the musk shrew This research fining was inserted in Anat.Rec. (Hoboken 290,2007) Achievement of nerves supplying cholecyst of human and musk shrew was inserted in Aorld J. Gastroenteral (13, 2007) Also, we make histological clarification, using electron microscope, and link up with academic researchers of the Molecular and Genetic Science. The result was inserted in Nature (Vol.446, 2007) We also coached master's student in order to clarigy arteries coursing in apex of the bladder, umbilicus, falciform ligament of liver ; round ligament of liver. This fruit of research was determined as graduation thesis in 2007. In all human donor bodies, using above noted research technology, we have first clarified arteries coursing from the abdominant wall to the liver, and existence of the allantoic stalk. We are providing to complete thesis. |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号:18590164, 研究期間(年度):2006–2007 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出典:「全胚免疫染色と分子生物学的手法による内臓と四肢の神経・血管・筋の形成と再生の解明」研究成果報告書 課題番号18590164 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) 本文データは著者版報告書より作成 |
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著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/search/?qm=60004660 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18590164/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18590164/185901642007kenkyu_seika_hokoku_gaiyo/ |