アジアの糖尿病性腎症の予後調査、予後関連因子解析、国際比較を目的とした。本邦の糖尿病性腎症の予後関連因子、予後判定のためのスコアリングを確立した（Wada, et al. Clin Exp Nephrol 2014）。これを用いて、アジアコホート間で比較調査を行った。日本腎臓学会、Asian Forum of CKD Initiativeと連携し、糖尿病性腎症のアジア共同研究体制を構築した。台湾2大学のコホートで予後評価を行った。予後関連因子としてのアルブミン尿の重要性、本邦の予後推定スコアリングの有効性を示した。アジアの他コホートを用いた国際調査も進行している。
This study was aimed to compare outcomes and their related risk factors in patients with diabetic nephropathy among Asian countries based on our Japanese database in patients with diabetic nephropathy. Our study strongly showed that the presence of macroalbuminuria increased the adjusted hazard ratios for kidney event (Wada, et al. Clin Exp Nephrol 2014). Diabetic nephropathy score, based on the prognostic factors, well predicted incidence rates per 1000 patient/year for kidney event, cardiovascular events and death. Then, we have established international collaborative research team on diabetic nephropathy among Asian countries. The results of advanced diabetic patients from Taiwanese diabetic cohorts confirmed that albuminuria was of importance for kidney prognosis. In addition, these showed that related prognostic risk factors from our Japanese database were closely relevant to those of Asian diabetic nephropathy patients.
アジア系人種における糖尿病性腎症の予後調査と予後規定因子の国際比較研究
.png)
ME-PR-WADA-T-kaken 2015-6p.pdf
(219.41KB)
