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Expression of the adhesion molecule spermatogenic immunoglobulin superfamily (SgIGSF) in mouse tissues
http://hdl.handle.net/2297/6773
http://hdl.handle.net/2297/6773a926c84a-2aa1-438e-ad0a-15ca8b7fcd7e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AA00508022-WAKAYAMA-T-365.pdf (359.9 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Expression of the adhesion molecule spermatogenic immunoglobulin superfamily (SgIGSF) in mouse tissues | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Wakayama, Tomohiko
× Wakayama, Tomohiko× Koami, Hiroyuki× Yamamoto, Miyuki× Iseki, Shoichi |
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| 提供者所属 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 金沢大学大学院医学系研究科がん細胞学 | |||||
| 書誌情報 |
Acta Histochemica et Cytochemica 巻 33, 号 4, p. 365-371, 発行日 2004-01-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0044-5991 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508022 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1267/ahc.37.365 | |||||
| 出版者 | ||||||
| 出版者 | 日本組織細胞化学会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Spermatogenic immunoglobulin superfamily (SgIGSF) is an adhesion molecule originally isolated from adult mouse testis. In the testis, SgIGSF is expressed specifically in spermatogenic cells and may be involved in spermatogenesis. SgIGSF may also be involved in synapse formation and tumor suppression. In the present study, we examined the expression and cellular localization of SgIGSF in the entire adult mouse organs and tissues using Western blot analysis and immunohistochemistry at light and electron microscopic levels. Western blot analysis revealed that SgIGSF is expressed not only in the testis but also in the liver, lung, and nervous system including the cerebrum, cerebellum and sciatic nerve. The nervous system as well as testis showed multiple immunoreactive bands ranging from 45 to 100 kDa, whereas the liver and lung showed a single 100 kDa band. Immunohistochemisfry demonstrated that in the nervous system, SgIGSF is localized to the membranes of synapses, axons and Schwann cells. In contrast, in the lung and liver SgIGSF was localized to the membranes of apposing respiratory epithelial cells, hepatocytes and biliary epithelial cells. These results suggested that SgIGSF plays multiple physiological roles in the adult mouse as an adhesion molecule | |||||
| 権利 | ||||||
| 権利情報 | 日本組織細胞化学会の許諾を得て登録 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.jstage.jst.go.jp/article/ahc/37/6/37_365/_article | |||||
