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  1. C. 医薬保健学域; 医学類・薬学類・医薬科学類・保健学類
  2. c 10. 学術雑誌掲載論文(医・保健)
  3. 1. 査読済論文(医学・保健)

An experimental study of use of absorbable plate in combination with self-setting α-tricalcium phosphate for orthognathic surgery

http://hdl.handle.net/2297/25768
http://hdl.handle.net/2297/25768
bb7d4d67-80a1-4ffd-8148-7a6ef453282c
名前 / ファイル ライセンス アクション
ME-PR-UEKI-K-560.pdf ME-PR-UEKI-K-560.pdf (1.2 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-10-03
タイトル
タイトル An experimental study of use of absorbable plate in combination with self-setting α-tricalcium phosphate for orthognathic surgery
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Okabe, Katsuhiko

× Okabe, Katsuhiko

WEKO 21290

Okabe, Katsuhiko

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Ueki, Koichiro

× Ueki, Koichiro

WEKO 575
e-Rad 40313663
研究者番号 40313663

Ueki, Koichiro

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Marukawa, Kohei

× Marukawa, Kohei

WEKO 21291

Marukawa, Kohei

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Mukozawa, Aya

× Mukozawa, Aya

WEKO 21292

Mukozawa, Aya

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Miyazaki, Mao

× Miyazaki, Mao

WEKO 21293

Miyazaki, Mao

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Nakagawa, Kiyomasa

× Nakagawa, Kiyomasa

WEKO 496
研究者番号 30155676

Nakagawa, Kiyomasa

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提供者所属
内容記述タイプ Other
内容記述 金沢大学医薬保健研究域医学系
書誌情報 Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology

巻 110, 号 5, p. 560-569, 発行日 2010-11-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 1079-2104
NCID
収録物識別子タイプ NCID
収録物識別子 AA11032296
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.1016/j.tripleo.2010.02.033
出版者
出版者 Elsevier
抄録
内容記述タイプ Abstract
内容記述 Objective: The purpose of this study was to histologically and immunohistochemically evaluate bone formation using both self-setting α-tricalcium phosphate (α-TCP; Biopex) and absorbable plate (Super Fixsorb-MX) in rabbit cranium bone. Study design: Twelve adult male Japanese white rabbits (12-16 wk, 2.5-3.0 kg) were used. The surgical defects were made in the nasal bone of a rabbit, and Biopex was implanted in the left side and no material in the right side. Two-hole absorbable plate and 2 screws (Super Fixsorb-MX) were fixed across the defect in each side. The rabbits were killed at 1, 4, 12, and 24 weeks after surgery, and formalin-fixed specimens were embedded in acrylic resin. The specimens were stained with hematoxylin and eosin. For immunohistochemical analysis, the specimens were treated with bone morphogenetic protein 2 (BMP-2) antibodies. Finally, these were evaluated microscopically. Results: New bone formation was observed in the region of absorbable plate and nasal membrane after >4 weeks. The area of new bone with Biopex was significantly larger than that of the control side after 1, 4, and 12 weeks (P < .05). The number of BMP-2stained cells in the experimental side was significantly larger than in the control side after 4 and 12 weeks (P < .05). Conclusion: This study suggests that the use of absorbable plate (Super Fixsorb-MX) in combination with Biopex could be useful and that both of Super Fixsorb-MX and Biopex could provide adequate bone regeneration. © 2010 Mosby, Inc.
著者版フラグ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
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