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脳血管攣縮による中膜筋細胞壊死の病理
http://hdl.handle.net/2297/25183
http://hdl.handle.net/2297/251833305aafa-d207-4b62-add0-a8c7a4d9409c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-YAMASHIMA-T-335.pdf (1.2 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | 脳血管攣縮による中膜筋細胞壊死の病理 | |||||
| タイトル | ||||||
| タイトル | Pathology of myonecrosis following cerebral vasospasm | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
山嶋, 哲盛
× 山嶋, 哲盛× 林, 実× 佐藤, 一史× 早瀬, 秀男× 山本, 信二郎 |
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| 提供者所属 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 金沢大学医薬保健研究域医学系 | |||||
| 提供者所属 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 金沢大学附属病院脳神経外科 | |||||
| 書誌情報 |
Neurologia Medico-Chirurgica 巻 24, 号 5, p. 335-342, 発行日 1984-01-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0470-8105 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA0075470X | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.2176/nmc.24.335 | |||||
| 出版者 | ||||||
| 出版者 | 日本脳神経外科学会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Histological changes of the cerebral arteries taken from 3 patients who died of cerebral vasospasm after subarachnoid hemorrhage were investigated and compared with those of 10 dogs with experimental vasospasm induced by a subarachnoid injection of 0.15-0.20 mg/kg of epinephrine. The cerebral arteries of the human autopsy cases known to have undergone spasm exhibited a wide lumen with thin media resulting from necrosis of the smooth muscle cells. These necrotic smooth muscle cells were replaced by scattered, eosinophilic cellular debris, especially in the outer layer of the media. In the experimental study, the subarachnoid injection of epinephrine produced frank necrosis of the smooth muscle cells and marked dilatation of the arterial lumen, especially in 5 dogs, and was associated with hypothalamic infarctions and inflammatory swellings of small subarachnoid arteries. Dogs sacrificed artificially revealed myonecrotic changes that were uniformly and intensely stained with eosin, whereas those who died spontaneously revealed myonecrosis similar to human autopsy cases. It is suggested that myonecrosis might be formed as a result of prolonged, intense contraction induced by epinephrine as well as by vasoactive exudates from the hypothalamic lesions or the small subarachnoid arteries. | |||||
| 権利 | ||||||
| 権利情報 | Copyright© The Japan Neurosurgical Society | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://jns.umin.ac.jp/ | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.journalarchive.jst.go.jp/english/jnlabstract_en.php?cdjournal=nmc1959&cdvol=24&noissue=5&startpage=335 | |||||
