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Cytokine upregulation in tubulointerstitial nephritis associated with membranous nephropathy
http://hdl.handle.net/2297/29243
http://hdl.handle.net/2297/29243f36812ff-3260-48a0-87c9-935813364725
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-WADA-T-130.pdf (113.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Cytokine upregulation in tubulointerstitial nephritis associated with membranous nephropathy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Wada, Takashi
× Wada, Takashi× Yokoyama, Hitoshi× Sakai, Norihiko× Izumiya, Yoshiaki× Shimizu, Miho× Furuichi, Kengo× Segawa, Chikako× Misaki, Tsuguho× Kobayashi, Ken-ichi |
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| 書誌情報 |
Clinical and Experimental Nephrology 巻 3, 号 2, p. 130-132, 発行日 1999-01-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1342-1751 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11126935 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s101570050022 | |||||
| 出版者 | ||||||
| 出版者 | 日本腎臓学会 = Japanese Society of Nephrology | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We describe the upregulation of cytokines in a 45-year-old woman with tubulointerstitial nephritis and membranous nephropathy revealed by renal biopsy. She was treated with a combination of prednisolone and cyclosporin. Histological findings showed appreciable improvement, and urinary protein excretion was decreased from 15 g/day to 1 g/day. Elevated urinary levels of chemokines, interleukin (IL)-8 and monocyte chemotactic and activating factor (MCAF)/monocyte chemoattractant protein (MCP)-1, and serum levels of tumor necrosis factor (TNF)-α decreased during convalescence; 13 other patients with membranous nephropathy did not show elevation of these cytokines. These results suggest that the upregulation of these cytokines may participate in the pathogenesis of tubulointerstitial nephritis and that combination therapy of prednisolone and cyclosporin may be effective, possibly via inducing a decrease in these cytokines. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.springerlink.com/content/0598h7kthykdgenw/ | |||||
