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境界明瞭な網膜神経線維層欠損を有する正常眼圧緑内障における乳頭出血出現や網膜神経線維層欠損拡大と視野障害進行との関連
http://hdl.handle.net/2297/36189
http://hdl.handle.net/2297/3618935941c03-e1ef-40fe-a3fb-e8705c17cef5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-SUGIYAMA-K-839.pdf (5.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | 境界明瞭な網膜神経線維層欠損を有する正常眼圧緑内障における乳頭出血出現や網膜神経線維層欠損拡大と視野障害進行との関連 | |||||
| タイトル | ||||||
| タイトル | Relationship between the Frequency of Disc Hemorrhage and the Enlargement of Nerve Fiber Layer Defects and the Deterioration Speed of Visual Field Loss in Normal-tension Glaucoma with Wedge-shaped Nerve Fiber Layer Defects | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
新田, 耕治
× 新田, 耕治× 杉山, 和久× 棚橋, 俊郎 |
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| 書誌情報 |
日本眼科學会雜誌 = Journal of Japanese Ophthalmological Society 巻 115, 号 9, p. 839-847, 発行日 2011-09-10 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0029-0203 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00187157 | |||||
| 出版者 | ||||||
| 出版者 | 日本眼科学会 = Japanese Ophthalmological Society | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | 目的:正常眼圧緑内障(NTG)について乳頭出血(DH)出現および網膜神経線維層欠損(NFLD)拡大と視野障害進行との関連を検討すること. 対象と方法:3年以上(平均9.1年)経過観察した境界明瞭なNFLDを認めるNTG106例106眼を視野障害進行速度(MD slope, 半視野TD slope)やNFLD角度拡大速度について検討した. NFLD角度はカラー眼底写真を青成分のみを抽出した白黒写真に加工し, 乳頭中心と黄斑の中点を求め, 乳頭を中心とし中点までの距離を半径とした円がNFLDと交差する2点と乳頭中心とのなす角とした. 結果:DH出現頻度は51/106(48.1%)であり, DH回数は1.28±1.99(平均値±標準偏差)回であった. MD slopeがDH群は-0.30dB/yearで非DH群:-0.13dB/yearより有意に急峻で, NFLD拡大速度がDH群は1.90度/yearで非DH群:O.64度/yearより有意に急速だった. DH回数が増加するにつれTD slope(r=-0.263,p=0.0056)とNFLD拡大速度(r=0.410, p<0.0001)は有意に加速した. 結論:境界明瞭なNFLDを有するNTGにおいて, DH眼は非DH眼よりもNFLD拡大速度と視野障害進行速度が速く, かつ頻回にDHが出現した症例ほどその両者が加速した. Purpose : To examine progressive visual field loss in relation to disc hemorrhage (DH) and enlarged nerve fiber layer defects (NFLDs) in normal-tension glaucoma (NTG) . Subjects and Methods : There were 106 eyes of 106 NTG patients (mean follow-up : 9.1 years) with well-defined NFLD borders and at least 3 years of follow-up. Examination was performed on their rate of visual field loss (MD slope and hemifield TD slope) and their rate of NFLD angle enlargement. For the NFLD angle, we took color fundus photographs and converted color photos into black-white photos extracted the blue ingredient. The midpoint between the fovea and the disc center was determined. The center was established as the disc, and the distance to the midpoint was established as the radius of a circle. The NFLD angle was defined as the angle formed by the two points where this circle intersected the NFLD and a third point which was the disc center. Results : DH was seen in 51/106 (48.1%) cases and it occurred 1.28 ± 1.99 times. In the DH group, the MD slope was -0.30 dB/year, indicating a significantly faster rate of visual field loss than that of the non-DH group (-0.13 dB/year) ; the rate of NFLD enlargement was 1.90 degrees/year, indicating a significantly faster rate than that of the non-DH group at 0.64 degrees/year. As the occurrence of DH increased, the TD slope (r = -0.263, p = 0.0056) and the rate of NFLD enlargement (r = 0.410, p <0.0001) increased significantly. Conclusion : Examination was performed on NTG eyes with well-defined NFLD borders which were divided into the groups of with and without DH. The DH eyes had a faster rate of NFLD enlargement and faster progression of visual field loss compared with the non-DH eyes. In addition, the rate of NFLD enlargement and progression of visual field loss increased in the cases with frequent DHs. | |||||
| 権利 | ||||||
| 権利情報 | Copyright © Japanese Ophthalmological Society | |||||
| 権利URI | ||||||
| 権利情報 | http://www.nichigan.or.jp/index.jsp | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.nichigan.or.jp/member/journal/nggz/index.jsp | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://ci.nii.ac.jp/naid/10029528644/ | |||||
