WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "64a580d7-57f6-4a00-8eb2-606bce5c0db8"}, "_deposit": {"created_by": 3, "id": "13706", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "13706"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00013706", "sets": ["1134"]}, "author_link": ["22934", "22935", "92", "22936"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2012-01-01", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "403954", "bibliographicVolumeNumber": "2012", "bibliographic_titles": [{"bibliographic_title": "International Journal of Hepatology"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by immune mediated biliary damage and frequent appearance of autoantibodies against mitochondrial enzymes. There is almost no useful animal model that is globally recognized and routinely used, however, several unique animal models manifested the characteristic clinical and pathological features of human PBC within the last 5 years. Herein, we compare the pathological features of previously reported and newly introduced novel animal models of PBC. Knowledge and understanding of the strengths and the limitations of each animal model have led to the development of promising therapies and novel tools to characterize these clinical conditions. Moreover, suitability of the model for the intended purpose should be confirmed by further research and analysis.", "subitem_description_type": "Abstract"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Hindawi Publishing Corporation"}]}, "item_4_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1155/2012/403954", "subitem_relation_type_select": "DOI"}}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2090-3456", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Tsuneyama, Koichi"}], "nameIdentifiers": [{"nameIdentifier": "22934", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "10293341", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10293341"}]}, {"creatorNames": [{"creatorName": "Moritoki, Yuki"}], "nameIdentifiers": [{"nameIdentifier": "22935", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kikuchi, Kentaro"}], "nameIdentifiers": [{"nameIdentifier": "22936", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakanuma, Yasuni"}], "nameIdentifiers": [{"nameIdentifier": "92", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "10115256", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10115256"}, {"nameIdentifier": "10115256", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000010115256"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-10-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ME-PR-NAKANUMA-Y-403954.pdf", "filesize": [{"value": "515.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 515700.00000000006, "url": {"label": "ME-PR-NAKANUMA-Y-403954.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/13706/files/ME-PR-NAKANUMA-Y-403954.pdf"}, "version_id": "8659590d-c376-4f72-8e2c-81b370cec41c"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Pathological Features of New Animal Models for Primary Biliary Cirrhosis", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Pathological Features of New Animal Models for Primary Biliary Cirrhosis"}]}, "item_type_id": "4", "owner": "3", "path": ["1134"], "permalink_uri": "http://hdl.handle.net/2297/31482", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-10-03"}, "publish_date": "2017-10-03", "publish_status": "0", "recid": "13706", "relation": {}, "relation_version_is_last": true, "title": ["Pathological Features of New Animal Models for Primary Biliary Cirrhosis"], "weko_shared_id": -1}
Pathological Features of New Animal Models for Primary Biliary Cirrhosis
http://hdl.handle.net/2297/31482
http://hdl.handle.net/2297/3148225cfd0e5-c5d3-4d8b-9931-f177953c0e2f
名前 / ファイル | ライセンス | アクション |
---|---|---|
ME-PR-NAKANUMA-Y-403954.pdf (515.7 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Pathological Features of New Animal Models for Primary Biliary Cirrhosis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Tsuneyama, Koichi
× Tsuneyama, Koichi× Moritoki, Yuki× Kikuchi, Kentaro× Nakanuma, Yasuni |
|||||
書誌情報 |
International Journal of Hepatology 巻 2012, p. 403954, 発行日 2012-01-01 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2090-3456 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1155/2012/403954 | |||||
出版者 | ||||||
出版者 | Hindawi Publishing Corporation | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by immune mediated biliary damage and frequent appearance of autoantibodies against mitochondrial enzymes. There is almost no useful animal model that is globally recognized and routinely used, however, several unique animal models manifested the characteristic clinical and pathological features of human PBC within the last 5 years. Herein, we compare the pathological features of previously reported and newly introduced novel animal models of PBC. Knowledge and understanding of the strengths and the limitations of each animal model have led to the development of promising therapies and novel tools to characterize these clinical conditions. Moreover, suitability of the model for the intended purpose should be confirmed by further research and analysis. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |