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Intraductal papillary neoplasm of the bile duct in liver cirrhosis with hepatocellular carcinoma
http://hdl.handle.net/2297/31475
http://hdl.handle.net/2297/3147570af9157-e95f-4f60-86e1-20e324b09848
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-NAKANUMA-Y-1923.pdf (1.0 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Intraductal papillary neoplasm of the bile duct in liver cirrhosis with hepatocellular carcinoma | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Xu, Jing
× Xu, Jing× Sato, Yasunori× Harada, Kenichi× Yoneda, Norihide× Ueda, Teruyuki× Kawashima, Atsushi× Ooi, Akishi× Nakanuma, Yasuni |
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| 書誌情報 |
World Journal of Gastroenterology 巻 17, 号 4, p. 1923-1926, 発行日 2011-04-14 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1007-9327 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11690631 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.3748/wjg.v17.i14. | |||||
| 出版者 | ||||||
| 出版者 | WJG Press / Baishideng | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A case of intraductal papillary neoplasm of the bile duct (IPNB) arising in a patient with hepatitis B-related liver cirrhosis with hepatocellular carcinoma (HCC) is reported. A 76-year-old man was admitted to our hospital with recurrent HCC. Laboratory data showed that levels of carcinoembryonic antigen and carbohydrate antigen 19-9 were elevated. He died of progressive hepatic failure. At autopsy, in addition to HCCs, an intraductal papillary proliferation of malignant cholan-giocytes with fibrovascular cores was found in the dilated large bile ducts in the left lobe, and this papillary carcinoma was associated with an invasive mucinous carcinoma (invasive IPNB). Interestingly, extensive intraductal spread of the cholangiocarcinoma was found from the reactive bile ductular level to the interlobular bile ducts and septal bile ducts and to the large bile ducts in the left lobe. Neural cell adhesion molecule, a hepatic progenitor cell marker, was detected in IPNB cells. It seems possible in this case that hepatic progenitor cells located in reactive bile ductules in liver cirrhosis may have been responsible for the development of the cholangiocarcinoma and HCC, and that the former could have spread in the intrahepatic bile ducts and eventually formed grossly visible IPNB. © 2011 Baishideng. All rights reserved. | |||||
| 権利 | ||||||
| 権利情報 | © 2011 Baishideng | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
