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  1. C. 医薬保健学域; 医学類・薬学類・医薬科学類・保健学類
  2. c 10. 学術雑誌掲載論文(医・保健)
  3. 1. 査読済論文(医学・保健)

The outcomes of reconstruction using frozen autograft combined with iodine-coated implants for malignant bone tumors: Compared with non-coated implants

http://hdl.handle.net/2297/46534
http://hdl.handle.net/2297/46534
86ea0fa0-74d9-46ba-900e-1eb5bd36038a
名前 / ファイル ライセンス アクション
ME-PR-SHIRAI-T-735.pdf ME-PR-SHIRAI-T-735.pdf (583.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-10-03
タイトル
タイトル The outcomes of reconstruction using frozen autograft combined with iodine-coated implants for malignant bone tumors: Compared with non-coated implants
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Shirai, Toshiharu

× Shirai, Toshiharu

WEKO 22249
研究者番号 20397186

Shirai, Toshiharu

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Tsuchiya, Hiroyuki

× Tsuchiya, Hiroyuki

WEKO 151
e-Rad 40227434
金沢大学研究者情報 40227434
研究者番号 40227434

Tsuchiya, Hiroyuki

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Terauchi, Ryu

× Terauchi, Ryu

WEKO 1014
金沢大学研究者情報 20575154
研究者番号 20575154

Terauchi, Ryu

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Tsuchida, Shinji

× Tsuchida, Shinji

WEKO 23333

Tsuchida, Shinji

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Mizoshiri, Naoki

× Mizoshiri, Naoki

WEKO 23334

Mizoshiri, Naoki

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Igarashi, Kentaro

× Igarashi, Kentaro

WEKO 23335

Igarashi, Kentaro

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Miwa, Shinji

× Miwa, Shinji

WEKO 23336

Miwa, Shinji

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Takeuchi, Akihiko

× Takeuchi, Akihiko

WEKO 22247
e-Rad 70512218
金沢大学研究者情報 70512218
研究者番号 70512218

Takeuchi, Akihiko

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Kimura, Hiroaki

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WEKO 1347
e-Rad 60363074
金沢大学研究者情報 60363074
研究者番号 60363074

Kimura, Hiroaki

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Hayashi, Katsuhiro

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WEKO 22250
e-Rad 80507054
金沢大学研究者情報 80507054
研究者番号 80507054

Hayashi, Katsuhiro

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Yamamoto, Norio

× Yamamoto, Norio

WEKO 22248
e-Rad 90332668
金沢大学研究者情報 90332668
研究者番号 90332668

Yamamoto, Norio

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Kubo, Toshikazu

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WEKO 953
金沢大学研究者情報 20178031
研究者番号 20178031

Kubo, Toshikazu

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書誌情報 Japanese Journal of Clinical Oncology

巻 46, 号 8, p. 735-740, 発行日 2016-08-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 0368-2811
NCID
収録物識別子タイプ NCID
収録物識別子 AA00690866
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.1093/jjco/hyw065
出版者
出版者 Oxford University Press
抄録
内容記述タイプ Abstract
内容記述 Objective: We perform reconstruction using frozen tumor bone treated by liquid nitrogen after excision of malignant bone tumors. To prevent post-operative infection, we use iodine-coated implants that we developed. The purpose of this study is to compare the outcome of reconstruction using frozen autograft with non-coated implants (group N) and iodine-coated implants (group I).Methods: Sixty-two patients were included in group N. The mean age was 31.9 ± 2.3 years. A total of 20 patients died and two were lost to follow-up, averaging 20.0 ± 2.9 months post-operatively, leaving 40 patients available for an assessment at a mean of 79.1 ± 5.8 months post-operatively. There were 38 patients in group I. The mean age was 29.8 ± 3.9 years. The mean follow-up period was 32.1 ± 3.0 months. All patients were alive at the latest follow-up. Survival of frozen bone was determined by Kaplan-Meier analysis.Results: In group N, survival of frozen bone was 80.7 ± 6.0% and 57.4 ± 10.2% at 5 and 10 years, respectively. Complications were encountered in 31 of 62 patients (50.0%), including deep infection in 10 (16.1%), fracture in 11 (17.7%), local soft-tissue recurrence in 6 (9.7%) and bone absorption in 4 (6.5%). In group I, survival of frozen bone was 86.7 ± 6.3% at 5 years. Complications were encountered in 8 of 38 patients (21.1%), including deep infection in one (2.6%), fracture in four (10.5%), local soft-tissue recurrence in two (5.3%) and bone absorption in one (2.6%). There was a significantly lower infection rate in group I (P = 0.032).Conclusion: Reconstruction using frozen autograft combined with iodine-coated implants for patients with malignant bone tumor is very useful method in which good limb function can be gained with minimized risk of infection. © The Author 2016. Published by Oxford University Press. All rights reserved.
内容記述
内容記述タイプ Other
内容記述 Article number hyw065 / Embargo Period 6 months
著者版フラグ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
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