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The effect of reloading on disuse muscle atrophy: Time course of hypertrophy and regeneration focusing on the myofiber cross-sectional area and myonuclear change
http://hdl.handle.net/2297/34705
http://hdl.handle.net/2297/34705fe446d74-d3fe-4acb-baa3-b822f307bc9b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-YAMAZAKI-T-1.pdf (695.9 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | The effect of reloading on disuse muscle atrophy: Time course of hypertrophy and regeneration focusing on the myofiber cross-sectional area and myonuclear change | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Zushi, Kazumi
× Zushi, Kazumi× Yamazaki, Toshiaki |
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| 書誌情報 |
Journal of the Japanese Physical Therapy Association 巻 15, 号 1, p. 1-8, 発行日 2012-01-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1344-1272 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11338558 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1298/jjpta.Vol15_001 | |||||
| 出版者 | ||||||
| 出版者 | The Japanese Physical Therapy Association = 日本理学療法士協会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The purpose of this study was to investigate the effect of reloading on atrophied muscle and the time course of hypertrophy and regeneration. Forty-nine male Wistar rats were randomly assigned to groups for hindlimb suspension (HS), hindlimb suspension and reloading (R), or control (C0). Rats in the HS group were suspended for 14 days. Rats in the R group were randomly divided into fi ve subgroups for different post-hindlimb-suspension recovery times. Briefl y, each subgroup was suspended for 14 days and given 1 day of reloading (R1), 3 days of reloading (R3), 7 days of reloading (R7), 10 days of reloading (R10), or 14 days of reloading (R14). Myonuclear numbers were signifi cantly decreased in the groups with hindlimb suspension and 1 day and 3 days of reloading compared with that in the control group. We focused on the processes of change of mean myofi ber cross-sectional area and myonuclear domain size; the degrees of increase of both indexes were limited until 3 days of reloading, and signifi cantly increased after 7 days of reloading. An important fi nding of the current study was that the processes of muscle hypertrophy and regeneration did not show uniform change. In addition, there were differences in the ratio of increase among the stages of hypertrophy and regeneration. Therefore, consideration of the duration and method of physiotherapeutic intervention for atrophied muscle on the basis of the process of hypertrophy and regeneration is needed to provide more effective physiotherapy. | |||||
| 権利 | ||||||
| 権利情報 | Copyright © 2012 by the Japanese Physical Therapy Association | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.japanpt.or.jp/ | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/article/jjpta/15/1/15_Vol15_001/_article | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://japanlinkcenter.org/JST.JSTAGE/jjpta/Vol15_001 | |||||
