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Comparison of the Cutaneous Wound Healing of Ovariectomized Mouse at 12 Weeks with That of SHAM and Estrogen-Administered Mice
http://hdl.handle.net/2297/38465
http://hdl.handle.net/2297/3846561f00cd7-5e29-4014-9286-f6563663b369
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-NAKATANI-T-484258.pdf (2.5 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Comparison of the Cutaneous Wound Healing of Ovariectomized Mouse at 12 Weeks with That of SHAM and Estrogen-Administered Mice | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Mukai, Kanae
× Mukai, Kanae× Miyasaka, Yuriko× Takata, Kana× Urai, Tamae× Nakajima, Yukari× Komatsu, Emi× Sugama, Junko× Nakatani, Toshio |
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| 書誌情報 |
Journal of Hormones 巻 2014, p. 484258-1-484258-6, 発行日 2014-07-07 |
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| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1155/2014/484258 | |||||
| 出版者 | ||||||
| 出版者 | Hindawi Publishing Corporation | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The aim of this experiment was to investigate the effect of 17-estradiol on cutaneous wound healing in 12-week ovariectomized (OVX) female mice. Eight-week-old female mice were divided into three groups: administration of 17-estradiol after OVX (OVX + 17-estradiol), OVX, and sham (SHAM). Four weeks after surgery, the mice received two full-thickness cutaneous wounds. 17-Estradiol at 0.01 g/day was administered on the backs of mice in the OVX + 17-estradiol group every day. Plasma 17-estradiol level in the OVX + 17-estradiol group was thus significantly higher than in the SHAM and OVX groups, but there was no significant difference between SHAM and OVX groups. The ratio of wound area was not significantly different among the three groups. However, the period required to reach a ratio of wound area of 0.15 in the OVX + 17-estradiol group was significantly shorter than in the SHAM and OVX groups. These results indicate that cutaneous wound healing in young OVX mice was promoted by the administration of 17-estradiol compared with that in SHAM and OVX mice without such administration, but there was no difference between the latter two groups that did not differ in 17-estradiol level. | |||||
| 権利 | ||||||
| 権利情報 | Copyright © 2014 Kanae Mukai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.hindawi.com/journals/jhor/2014/484258/abs/ | |||||
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| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.hindawi.com/ | |||||
