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A method for assessing metabolic information on liver and bone marrow by use of double gradient-echo with spectral fat suppression
http://hdl.handle.net/2297/39852
http://hdl.handle.net/2297/3985229a20abc-96fd-4c1c-bf10-1802943902d8
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-KASAI-H-211.pdf (3.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | A method for assessing metabolic information on liver and bone marrow by use of double gradient-echo with spectral fat suppression | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Kasai, Harumasa
× Kasai, Harumasa× Miyati, Tosiaki× Kawai, Tatsuya× Kan, Hirohito× Kawano, Makoto× Shibamoto, Yuta |
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| 書誌情報 |
Radiological Physics and Technology 巻 7, 号 2, p. 211-216, 発行日 2014-07-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1865-0341 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s12194-013-0254-x | |||||
| 出版者 | ||||||
| 出版者 | Springer-Verlag | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Our aim in this study was to create a noninvasive and practical method for evaluating metabolic information on the liver (iron content and lipid infiltration) and spine (bone mineral density and marrow fat degeneration) using double gradient-echo with and without the spectral fat suppression technique (double-GRE-FS). We arranged phantoms made of various concentrations of superparamagnetic iron oxide solution adjacent to neutral fat to obtain slice planes with various fat fractions using the partial volume effect. We obtained double-GRE-FS images and calculated the T2* values. The fat fraction was calculated from signal intensities of double-GRE-FS images after T2* decay, baseline, and slope corrections. We assessed the fat fraction and the relationship between R2* of the water component and the iron concentration. In addition, we evaluated those values in human bone marrow and liver, including a patient with liver steatosis. The actual fat fraction value was consistent with the fat fraction obtained with the double-GRE-FS method, and the calculated fat fraction was unaffected by the iron concentration. There was a strong positive correlation between R 2* of the water component and the iron concentration. There was a negative correlation between the fat fraction and the bone mineral density, and the R2* was correlated with the bone mineral density. The calculated fat fraction in the liver steatosis patient was significantly higher than that in healthy volunteers. The double-GRE-FS makes it possible to assess the fat fraction and R2* simultaneously, and to obtain metabolic information on the liver and bone marrow. © 2014 Japanese Society of Radiological Technology and Japan Society of Medical Physics. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
