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Reverse vessel remodeling but not coronary plaque regression could predict future cardiovascular events in acs patients with intensive statin therapy - The extended JAPAN-ACS study -
https://doi.org/10.24517/00014370
https://doi.org/10.24517/000143706219eef7-94f8-413f-80e7-debe60b2391b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-YAMAGISHI-M-825.pdf (1.6 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2018-06-15 | |||||
| タイトル | ||||||
| タイトル | Reverse vessel remodeling but not coronary plaque regression could predict future cardiovascular events in acs patients with intensive statin therapy - The extended JAPAN-ACS study - | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| ID登録 | ||||||
| ID登録 | 10.24517/00014370 | |||||
| ID登録タイプ | JaLC | |||||
| 著者 |
Miyauchi, Katsumi
× Miyauchi, Katsumi× Daida, Hiroyuki× Morimoto, Takeshi× Hiro, Takafumi× Kimura, Takeshi× Nakagawa, Yoshihisa× Yamagishi, Masakazu× Ozaki, Yukio× Kadota, Kazushige× Kimura, Kazuo× Hirayama, Atsushi× Kimura, Kazumi× Hasegawa, Yasuhiro× Uchiyama, Shinichiro× Matsuzaki, Masunori× for the JAPAN-ACS Investigators |
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| 書誌情報 |
Circulation journal 巻 76, 号 4, p. 825-832, 発行日 2012-03-23 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1346-9843 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11591968 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1253/circj.CJ-12-0135 | |||||
| 出版者 | ||||||
| 出版者 | Japanese Circulation Society = 日本循環器学会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: The JAPAN-ACS study demonstrated that statins significantly reduced coronary plaque volume in patients with acute coronary syndrome (ACS). The clinical implications of plaque regression for clinical outcomes in ACS patients has not been established. The Extended JAPAN-ACS study was conducted to evaluate the relationship between coronary plaque regression and long-term clinical outcome, and to explore the factors associated with cardiovascular events. Methods and Results: Patients with intravascular ultrasound (IVUS) data at both enrollment and follow-up in the JAPAN-ACS study were enrolled and observed for at least 3 years. Patients were divided into lesser and greater coronary plaque regression groups. The primary endpoint was defined as a composite of the following events: cardiovascular death, nonfatal myocardial infarction, nonfatal cerebral infarction, and unstable angina. The median value of the percent change in plaque volume, 18.0%, was used as a cutoff point. There were 4 primary events (3.4%) in the lesser regression group, and 2 events (1.7%) in the greater regression group (P=0.4). Cumulative secondary cardiovascular events did not differ between the 2 groups. Multivariate analysis identified the high-density lipoprotein cholesterol (HDL-C) at baseline and the % change of the external elastic membrane volume as independent risk factors of cardiovascular events. Conclusions: Coronary plaque regression induced by an intensive statin regimen did not predict future cardiovascular events in ACS patients. Rather, the baseline HDL-C level and reverse vessel remodeling might serve as predictors for cardiovascular events. (Circ J 2012; 76: 825-832) | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 出版者照会後に全文公開 | |||||
| 権利 | ||||||
| 権利情報 | Copyright © 2012 THE JAPANESE CIRCULATION SOCIETY | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/browse/circj | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.j-circ.or.jp/english/ | |||||
