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The roles of orexins in sleep/wake regulation
http://hdl.handle.net/2297/48430
http://hdl.handle.net/2297/4843017d62588-74e3-48b5-8160-739de0a7a916
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-MIEDA-M-55.pdf (193.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-12-05 | |||||
| タイトル | ||||||
| タイトル | The roles of orexins in sleep/wake regulation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Mieda, Michihiro
× Mieda, Michihiro |
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| 書誌情報 |
Neuroscience Research 巻 118, p. 55-65, 発行日 2017-05-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0168-0102 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA10641652 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.neures.2017.03.015 | |||||
| 出版者 | ||||||
| 出版者 | Japan Neuroscience Society = 神経科学学会 / Elsevier | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Orexin A and orexin B are hypothalamic neuropeptides initially identified as endogenous ligands for two orphan G-protein coupled receptors (GPCRs). A deficiency of orexin signaling results in the sleep disorder narcolepsy-cataplexy in humans, dogs, and rodents, a sleep disorder characterized by excessive daytime sleepiness and cataplexy. Multiple approaches, including molecular genetic, electrophysiological, pharmacological, and neuroanatomical studies have suggested that orexins play critical roles in the maintenance of wakefulness by regulating the function of monoaminergic and cholinergic neurons that are implicated in the regulation of wakefulness. Here, I review recent advances in the understanding of how orexins regulate sleep/wakefulness and prevent narcolepsy. © 2017 Elsevier Ireland Ltd and Japan Neuroscience Society. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Embargo Period 12 months | |||||
| 権利 | ||||||
| 権利情報 | Copyright © 2017 Elsevier Ireland Ltd and Japan Neuroscience Society (CC BY NC-ND) | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.jnss.org/en/ | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.elsevier.com/locate/issn/01680102 | |||||
