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Patient weight-based acquisition protocols to optimize18F-FDG PET/CT image quality
http://hdl.handle.net/2297/30543
http://hdl.handle.net/2297/305435693edd2-0d13-48b9-ac8e-f346bed61d4d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-NAGAKI-A-72.pdf (486.5 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Patient weight-based acquisition protocols to optimize18F-FDG PET/CT image quality | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Nagaki, Akio
× Nagaki, Akio× Onoguchi, Masahisa× Matsutomo, Norikazu |
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| 書誌情報 |
Journal of Nuclear Medicine Technology 巻 39, 号 2, p. 72-76, 発行日 2011-06-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0091-4916 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00703709 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.2967/jnmt.110.081661 | |||||
| 出版者 | ||||||
| 出版者 | Society of Nuclear Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The choice of injected dose of 18F-FDG and acquisition time is important in obtaining consistently high-quality PET images. The aim of this study was to determine the optimal acquisition protocols based on patient weight for 3-dimensional lutetium oxyorthosilicate PET/CT. Methods: This study was a retrospective analysis of 76 patients ranging from 29 to 101 kg who were injected with 228-395.2 MBq of 18F-FDG for PET imaging. The study population was divided into 4 weightbased groups: less than 45 kg (group 1), 45-59 kg (group 2), 60-74 kg (group 3), and 75 kg or more (group 4). We measured the true coincidence rate, random coincidence rate, noise-equivalent counting rate (NECR), and random fraction and evaluated image quality by the coefficient of variance (COV) in the largest liver slices. Results: The true coincidence rate, random coincidence rate, and NECR significantly increased with increasing injected dose per kilogram (r 5 0.91, 0.83, and 0.90; all P < 0.01). NECR maximized at 10.11 MB/kg in underweight patients. The true coincidence rate differed significantly among the 4 groups, except for group 3 versus group 4 (P < 0.01). The ratio of the true coincidence rate for group 2 to groups 3 and 4 was 1.4 and 1.6, respectively. The average random fraction for all 4 groups was approximately 35%. The COV of the 4 groups differed for all pairs (P < 0.01). The COVs in overweight patients were larger than those in underweight patients, and image quality in overweight patients was poor. Conclusion: We modified acquisition protocols for 18F-FDG PET/CT according to the characteristics of a 3-dimensional lutetium orthosilicate PET scanner and PET image quality based on patient weight. The optimal acquisition time was approximately 1.4-1.6 times longer in overweight patients than in normal-weight patients. Estimation of optimal acquisition times using the true coincidence rate is more important than other variables in improving PET image quality. © 2011 by the Society of Nuclear Medicine, Inc. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Thesis of Nagaki, Akio / 長木 昭男 博士学位論文(金沢大学 / 大学院医薬保健学総合研究科) | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
