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Lectin binding of intrahepatic bile ducts and peribiliary glands in normal livers and hepatolithiasis
http://hdl.handle.net/2297/16863
http://hdl.handle.net/2297/16863e963106e-61cb-42e9-b77c-efe6e155798b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME0PR-NAKANUMA-Y-81.pdf (9.4 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Lectin binding of intrahepatic bile ducts and peribiliary glands in normal livers and hepatolithiasis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Saito, Katsuhiko
× Saito, Katsuhiko× Nakanuma, Yasuni |
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| 提供者所属 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 金沢大学医薬保健研究域医学系 | |||||
| 書誌情報 |
Tohoku Journal of Experimental Medicine 巻 160, 号 1, p. 81-92, 発行日 1990-01-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0040-8727 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00863920 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1620/tjem.160.81 | |||||
| 出版者 | ||||||
| 出版者 | 東北大学 : 東北ジャーナル刊行会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Histochemical features of the intrahepatic bile ducts and peribiliary glands were examined with five biotinylated lectins in 12 normal human livers and 12 livers with hepatolithiasis. There was a marked proliferation of peribiliary glands, especially mucous cells, in the stone-containing bile ducts. Based on the carbohydrate binding specificity for each lectin, it was found in both the normal and hepatolithiasis livers, that N-acetylglucosamine, N-acetylgalactosamine, D-galactose and L-focose were abundant in the mucous acinar cells of the intrahepatic peribiliary glands, and mannose (or glucose) was present exclusively in the serous acinar cells and surface lining epithelium. Considerable case to case and cell to cell variations, however, were noted in the expression of lectin binding activity. It has been shown that major monosaccharide components of biliary glycoproteins are N-acetylglucosamine, galactose and fucose. All of these carbohydrates were detected in the peribiliary glands, especially mucous acinar cells, in this study. Therefore, the peribiliary mucous cells are mainly responsible for the secretion of the glycoproteins with these carbohydrates into the hepatic bile, and may play a role in the calculi formation in the intrahepatic biliary tree. | |||||
| 権利 | ||||||
| 権利情報 | Copyright© Tohoku University Medical Press | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://journal.med.tohoku.ac.jp/ | |||||
| 関連URI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | http://dx.doi.org/10.1620/tjem.160.81 | |||||
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| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.journalarchive.jst.go.jp/jnlpdf.php?cdjournal=tjem1920&cdvol=160&noissue=1&startpage=81&lang=en&from=jnlabstract | |||||
