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  1. C. 医薬保健学域; 医学類・薬学類・医薬科学類・保健学類
  2. c 10. 学術雑誌掲載論文(医・保健)
  3. 2.査読済論文(薬)

Transfer of Polycyclic Aromatic Hydrocarbons to Fetuses and Breast Milk of Rats Exposed to Diesel Exhaust

http://hdl.handle.net/2297/29004
http://hdl.handle.net/2297/29004
cfce53e4-b12a-4903-b1f8-5aa9b9c2cc83
名前 / ファイル ライセンス アクション
PH-PR-HAYAKAWA-K-497.pdf PH-PR-HAYAKAWA-K-497.pdf (276.8 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-10-04
タイトル
タイトル Transfer of Polycyclic Aromatic Hydrocarbons to Fetuses and Breast Milk of Rats Exposed to Diesel Exhaust
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Tozuka, Yoshiko

× Tozuka, Yoshiko

WEKO 27585

Tozuka, Yoshiko

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Watanabe, Nobue

× Watanabe, Nobue

WEKO 27586

Watanabe, Nobue

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Osawa, Masanobu

× Osawa, Masanobu

WEKO 27587

Osawa, Masanobu

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Toriba, Akira

× Toriba, Akira

WEKO 66
e-Rad 50313680
金沢大学研究者情報 50313680
研究者番号 50313680

Toriba, Akira

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Kizu, Ryoichi

× Kizu, Ryoichi

WEKO 20795
e-Rad 80143915
研究者番号 80143915

Kizu, Ryoichi

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Hayakawa, Kazuichi

× Hayakawa, Kazuichi

WEKO 35
e-Rad 40115267
金沢大学研究者情報 40115267
研究者番号 40115267

Hayakawa, Kazuichi

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書誌情報 Journal of Health Science = 衛生化学

巻 50, 号 5, p. 497-502, 発行日 2004-10-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 1344-9702
NCID
収録物識別子タイプ NCID
収録物識別子 AA11316464
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.1248/jhs.50.497
出版者
出版者 Pharmaceutical Society of Japan = 日本薬学会
抄録
内容記述タイプ Abstract
内容記述 Polycyclic aromatic hydrocarbons (PAHs) were analyzed in maternal blood and fetuses from Fischer 344 rats exposed to diesel exhaust (DE) during pregnancy, and in breast milk from rats exposed to DE during pregnancy and lactation using high performance liquid chromatography with fluorescence detection. Concentrations of phenanthrene (Phe), anthracene (Ant) and benz[a]anthracene (BaA) were significantly higher in maternal blood of the DE group than those of the control group. Concentration of Phe in fetuses of the DE group was significantly higher than those of the control group. Concentrations of fluorene, Ant, fluoranthene (Flu), pyrene (Pyr), BaA and chrysene (Chr) tended to be higher in fetuses of the DE group. The levels of Ant, Flu, Pyr and Chr in breast milk from the DE group were significantly higher than those of the control group. These results indicate that PAHs taken into mother rat by the inhalation of DE are transferred into fetuses via placenta and into breast milk. This is the first report to clarify the transportation of inhaled PAHs into fetuses and breast milk from mother rats.
権利
権利情報 Copyright (c) 2004 by The Pharmaceutical Society of Japan
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
関連URI
識別子タイプ URI
関連識別子 http://www.pharm.or.jp/
関連URI
識別子タイプ URI
関連識別子 https://japanlinkcenter.org/JST.JSTAGE/jhs/50.497
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