| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-10-05 |
| タイトル |
|
|
タイトル |
Thallium transport and the evaluation of olfactory nerve connectivity between the nasal cavity and olfactory bulb |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| ID登録 |
|
|
ID登録 |
10.24517/00026578 |
|
ID登録タイプ |
JaLC |
| 著者 |
Kinoshita, Yayoi
Shiga, Hideaki
Washiyama, Kohshin
Ogawa, Daisuke
Amano, Ryohei
Ito, Makoto
Tsukatani, Toshiaki
Furukawa, Mitsuru
Miwa, Takaki
|
| 著者別表示 |
志賀, 英明
鷲山, 幸信
天野, 良平
伊藤, 真人
塚谷, 才明
古川, 仞
三輪, 高喜
|
| 提供者所属 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
金沢大学医学部附属病院耳鼻咽喉科 |
| 書誌情報 |
Chemical Senses
巻 33,
号 1,
p. 73-78,
発行日 2008-01-01
|
| ISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0379-864X |
| NCID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00142441 |
| DOI |
|
|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
10.1093/chemse/bjm066 |
| 出版者 |
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出版者 |
Oxford University Press |
| 抄録 |
|
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内容記述タイプ |
Abstract |
|
内容記述 |
Little is known regarding how alkali metal ions are transported in the olfactory nerve following their intranasal administration. In this study, we show that an alkali metal ion, thallium is transported in the olfactory nerve fibers to the olfactory bulb in mice. The olfactory nerve fibers of mice were transected on both sides of the body under anesthesia. A double tracer solution (thallium-201, 201Tl; manganese-54, 54Mn) was administered into the nasal cavity the following day. Radioactivity in the olfactory bulb and nasal turbinate was analyzed with gamma spectrometry. Auto radiographic images were obtained from coronal slices of frozen heads of mice administered with 201Tl or 54Mn. The transection of the olfactory nerve fibers was confirmed with a neuronal tracer. The transport of intranasal administered 201Tl/54Mn to the olfactory bulb was significantly reduced by the transection of olfactory nerve fibers. The olfactory nerve transection also significantly inhibited the accumulation of fluoro-ruby in the olfactory bulb. Findings indicate that thallium is transported by the olfactory nerve fibers to the olfactory bulb in mice. The assessment of thallium transport following head injury may provide a new diagnostic method for the evaluation of olfactory nerve injury. © The Author 2007. Published by Oxford University Press. All rights reserved. |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
HO-PR-SHIGA-H-73.pdf (1.5 MB)
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