Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2017-10-05 |
タイトル |
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タイトル |
Prediction of carotid artery in-stentrestenosis by quantitative assessment ofvulnerable plaque using computed tomography |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
ID登録 |
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ID登録 |
10.24517/00026936 |
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ID登録タイプ |
JaLC |
著者 |
Misaki, Kouichi
Uchiyama, Naoyuki
Mohri, Masanao
Hayashi, Yutaka
Ueda, Fumiaki
Nakada, Mitsutoshi
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著者別表示 |
見崎, 孝一
内山, 尚之
毛利, 正直
林, 裕
植田, 文明
中田, 光俊
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書誌情報 |
Journal of Neuroradiology
巻 43,
号 1,
p. 18-24,
発行日 2016-02-01
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ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0150-9861 |
NCID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA0025864X |
DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
10.1016/j.neurad.2015.09.002 |
出版者 |
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出版者 |
Elsevier |
抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background and purpose To assess the relationship between plaque volume evaluated by multidetector computed tomographic angiography (MDCT) and in-stent restenosis (ISR) after carotid artery stenting (CAS). Materials and methods From a retrospectively maintained database, data were collected for 52 patients with carotid artery stenosis treated with CAS between 2007 and 2012. We defined ISR of ≥ 50% as a peak systolic velocity ≥ 200 cm/s on echo-duplex scan. Carotid plaques were subdivided into four components according to radiodensity in Hounsfield units (HU) as follows: < 0, 0–60, 60–130, and > 600 HU. Risk factors that influenced ISR were compared using univariate and multivariate Cox regression analyses. Results During a median follow-up period of 36 months, ISR of ≥ 50% was detected in five patients (9.6%). In the univariate Cox proportional hazard regression analysis, renal insufficiency, coronary artery disease, total plaque volume, and plaque volumes with radiodensities < 0 and ≥ 600 HU increased the risk for ISR (P < 0.10). When the significant risk factors determined from the univariate analysis were subjected to a multivariate analysis, only the volumes of the plaque components with radiodensities < 0 HU independently predicted the development of ISR (hazard ratio: 1.041; 95% confidence interval: 1.006–1.078; P = 0.021). Conclusion Our data suggest that the high volume of the plaque components with radiodensities < 0 HU was independently associated with the increased risk of ISR after CAS. Quantitative and qualitative tissue characterizations of carotid plaques using MDCT might be a useful predictive tool of the development of ISR. |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Embargo Period 12 months |
権利 |
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権利情報 |
Copyright © 2016 Elsevier (CC-BY NC ND) |
著者版フラグ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |