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Trajectories of Postload Plasma Glucose in the Development of Type 2 Diabetes in Japanese Adults
https://doi.org/10.24517/00049541
https://doi.org/10.24517/00049541e5965f58-cfa5-4940-808e-84a20b62695f
| 名前 / ファイル | ライセンス | アクション |
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HO-PR-KOMETAN-M-5307523.pdf (903.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||
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| 公開日 | 2017-12-22 | |||||||||||||||||||
| タイトル | ||||||||||||||||||||
| タイトル | Trajectories of Postload Plasma Glucose in the Development of Type 2 Diabetes in Japanese Adults | |||||||||||||||||||
| 言語 | ||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||
| ID登録 | ||||||||||||||||||||
| ID登録 | 10.24517/00049541 | |||||||||||||||||||
| ID登録タイプ | JaLC | |||||||||||||||||||
| 著者 |
Oka, Rie
× Oka, Rie× Shibata, Kyoko× Sakurai, Masaru× Kometani, Mitsuhiro× Yamagishi, Masakazu× Yoshimura, Kenichi× Yoneda, Takashi |
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| 著者別表示 |
大家, 理恵
× 大家, 理恵
× 柴田, 恭子
× 櫻井, 勝
× 米谷, 充弘
× 山岸, 正和
× 吉村, 健一
× 米田, 隆
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| 提供者所属 | ||||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||||
| 内容記述 | 金沢大学附属病院研修医・専門医総合教育センター | |||||||||||||||||||
| 書誌情報 |
Journal of Diabetes Research 巻 2017, p. 5307523, 発行日 2017-09-14 |
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| ISSN | ||||||||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||||||||
| 収録物識別子 | 2314-6745 | |||||||||||||||||||
| DOI | ||||||||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||
| 関連識別子 | 10.1155/2017/5307523 | |||||||||||||||||||
| 出版者 | ||||||||||||||||||||
| 出版者 | Hindawi Limited | |||||||||||||||||||
| 抄録 | ||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||
| 内容記述 | We aimed to clarify how the trajectories of 1-hour postload plasma glucose (PG) and 2-hour PG were different in the development of type 2 diabetes. Using data of repeated health checkups in Japanese workers from April 2006 to March 2016, longitudinal changes of fasting, 1-hour, and 2-hour PG on the oral glucose tolerance test were analyzed with a linear mixed effects model. Of the 1464 nondiabetic subjects at baseline, 112 subjects progressed to type 2 diabetes during the observation period (progressors). In progressors, 1-hour PG and 2-hour PG showed gradual increases with slopes of 1.33 ± 0.2 and 0.58 ± 0.2 mg/dL/year, respectively, followed by a steep increase by which they attained diabetes. Until immediately before the diabetes transition, age- and sex-adjusted mean level of 2-hour PG was 149 ± 2.7 mg/dL, 34 ± 2.7 (30%) higher compared to nonprogressors, while that of 1-hour PG was 206 ± 4.1 mg/dL, 60 ± 4.3 mg/dL (41%) higher compared to nonprogressors. In conclusion, diabetes transition was preceded by a mild elevation of 2-hour PG for several years or more. The elevation in 1-hour PG was larger than that of 2-hour PG until immediately before the transition to diabetes. © 2017 Rie Oka et al. | |||||||||||||||||||
| 内容記述 | ||||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||||
| 内容記述 | Embargo Period 12 months | |||||||||||||||||||
| 権利 | ||||||||||||||||||||
| 権利情報 | Copyright © 2017 Rie Oka et al. | |||||||||||||||||||
| 著者版フラグ | ||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||
