| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2018-05-07 |
| タイトル |
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|
タイトル |
Multifocal human papillomavirus detection in palatine and pharyngeal tonsils |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| ID登録 |
|
|
ID登録 |
10.24517/00050456 |
|
ID登録タイプ |
JaLC |
| 著者 |
Murono, Shigeyuki
Yoshida, Hiroshi
Kobayashi, Tetsuro
Kawase, Tomotaka
Kikuchi, Daisuke
Suzuki, Toshihiko
Nakanishi, Yosuke
Endo, Kazuhira
Kimura, Hiroaki
Wakisaka, Naohiro
Yoshizaki, Tomokazu
|
| 著者別表示 |
室野, 重之
中西, 庸介
遠藤, 一平
脇坂, 尚宏
吉崎, 智一
|
| 提供者所属 |
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|
内容記述タイプ |
Other |
|
内容記述 |
金沢大学医薬保健研究域医学系 |
| 書誌情報 |
Acta Oto-Laryngologica
巻 138,
号 5,
p. 483-486,
発行日 2018-05-04
|
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0001-6489 |
| NCID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0050923X |
| DOI |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
10.1080/00016489.2017.1408143 |
| 出版者 |
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出版者 |
Taylor and Francis Ltd |
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: Multifocal human papillomavirus (HPV) infection into the palatine and pharyngeal tonsils, which might be linked to a second primary tumor of HPV-positive oropharyngeal cancer (OPC), was investigated. Patients and methods: One hundred and five patients with various head and neck diseases including 14 patients with OPC were enrolled in this study. Swabs from the palatine and pharyngeal tonsils were collected in each individual, and auto-nested GP5+/GP6+ PCR for HPV DNA was performed. Results: HPV DNA was detected in the palatine tonsil or the pharyngeal tonsil in a small subset of upper respiratory tract cancer other than OPC (URTC) and non-cancer diseases. Furthermore, HPV DNA was detected in both the palatine and pharyngeal tonsils in the same individual in 2 of 48 (4%) URTC cases, and 1 of 43 (2%) non-cancer cases. On the other hand, p16-positive OPC cases demonstrated a higher HPV DNA detection rate (4 of 9, 44.4%) compared with other disease groups. Conclusion: HPV DNA detection in both the palatine and pharyngeal tonsils in the same individual, especially in HPV-OPC, suggested the ability of HPV to infect tonsillar tissues of Waldeyer’s ring multifocally. © 2017 Acta Oto-Laryngologica AB (Ltd) |
| 内容記述 |
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|
内容記述タイプ |
Other |
|
内容記述 |
Embargo Period 12 months |
| 権利 |
|
|
権利情報 |
Copyright © 2017 Acta Oto-Laryngologica AB (Ltd) |
| 著者版フラグ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
ME-PR-MURONO-S-483.pdf (245.5 kB)
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