| Item type |
学術雑誌論文 / Journal Article_04(1) |
| 公開日 |
2019-01-07 |
| タイトル |
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タイトル |
Additive Prognostic Value of Carotid Plaque Score to Enhance the Age, Creatinine, and Ejection Fraction Score in Patients with Acute Coronary Syndrome |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| ID登録 |
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ID登録 |
10.24517/00053009 |
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ID登録タイプ |
JaLC |
| 著者 |
Nakahashi, Takuya
Tada, Hayato
Sakata, Kenji
Nomura, Akihiro
Ohira, Miho
Mori, Mika
Takamura, Masayuki
Hayashi, Kenshi
Yamagishi, Masakazu
Kawashiri, Masa-aki
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| 著者別表示 |
多田, 隼人
坂田, 憲治
野村, 章洋
大平, 美穂
森, 三佳
高村, 雅之
林, 研至
山岸, 正和
川尻, 剛照
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| 提供者所属 |
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内容記述タイプ |
Other |
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内容記述 |
金沢大学附属病院循環器内科 |
| 書誌情報 |
Journal of Atherosclerosis and Thrombosis
巻 25,
号 8,
p. 709-719,
発行日 2018
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1340-3478 |
| NCID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11018976 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.5551/jat.42317 |
| 出版者 |
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出版者 |
日本動脈硬化学会 = Japan Atherosclerosis Society |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Aim: To assess whether combining measurements obtained from carotid ultrasonography in addition to the age, creatinine, and ejection fraction (ACEF) score would improve the predictive ability of outcome in patients with acute coronary syndrome (ACS).
\nMethods: We examined 264 patients with ACS (194 men; mean age: 68±11 years) who underwent percutaneous coronary intervention. The carotid plaque score (cPS) and intima–media thickness (cIMT) were determined by carotid ultrasonography. The modified ACEF score was calculated using the following formula: (age/left ventricular ejection fraction) ＋1 point for every 10 mL/min reduction in creatinine clearance below 60 mL/min per 1.73 m2. The endpoint of this study was major adverse cardiovascular and cerebrovascular events (MACEs), defined as all-cause death, myocardial infarction, stoke, and target vessel revascularization.
\nResults: During the median 4-year follow-up, there were 121 incidents of MACEs. Multivariate Cox proportional hazard regression analysis revealed that cPS ≥9.8 (hazard ratio [HR], 1.52; 95% confidence interval [CI], 1.01–2.31) and ACEF score ≥1.20 (HR, 1.62; 95% CI, 1.11–2.39) were significantly associated with MACEs, whereas cIMT was not. When the new combined risk score was calculated by multiplying the cPS by the modified ACEF score, the freedom from MACEs at 5 years was 71% and 31% for the lower and higher scores, respectively (p＜0.001). The area under the receiver-operating characteristic curve for MACEs for the ACEF score, cPS, and combined risk score were 0.65, 0.66, and 0.71, respectively (p＜0.05).
\nConclusion: The cPS offers an incremental predictive value when combined to the simple ACEF score in ACS. |
| 内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
This article distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License. |
| 権利 |
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権利情報 |
Copyright © 日本動脈硬化学会 Japan Atherosclerosis Society |
| 著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連URI |
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識別子タイプ |
URI |
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関連識別子 |
https://www.jstage.jst.go.jp/browse/jat/-char/ja |
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関連名称 |
https://www.jstage.jst.go.jp/browse/jat/-char/ja |
| 関連URI |
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識別子タイプ |
URI |
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関連識別子 |
http://www.j-athero.org/ |
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関連名称 |
http://www.j-athero.org/ |
ME-PR-TADA-H-709.pdf (622.7 kB)
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